PMID: 7014653Mar 1, 1981Paper

Immunoperoxidase localisation of human placental lactogen: a marker for the placental origin of the giant cells in 'syncytial endometritis' of pregnancy

Journal of Clinical Pathology
E HeydermanS W Rosen

Abstract

One hundred endometrial biopsies of various histological patterns, and material from 10 tubal pregnancies together with their associated uterine decidua, were examined for the presence of human placental lactogen using affinity-purified first and second antibodies and an indirect immunoperoxidase technique. Positive cells in endometrial curettings were seen only in association with an intrauterine pregnancy and morphologically resembled syncytiotrophoblast. Decidua associated with tubal pregnancy, pseudodecidua in progestogen-treated patients, and proliferative, secretory, and basal endometria were all negative. An immunoperoxidase stain for human placental lactogen is a useful marker for intrauterine pregnancy and supports the placental origin of the syncytial giant cells in so-called 'syncytial endometritis'. The technique is of potential value in those endometrial biopsies where pregnancy is suspected but no villi are seen.

References

Jul 10, 1976·Lancet·E Heyderman, A M Neville
Dec 23, 1978·Lancet·E Heyderman, A M Neville
Oct 1, 1979·Journal of Clinical Pathology·E Heyderman
Apr 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·W B Watkins
Jan 1, 1977·Journal of Clinical Pathology·C H HorneG D Milne
Nov 1, 1976·British Journal of Obstetrics and Gynaecology·G Gau, T Chard
Jan 15, 1977·American Journal of Obstetrics and Gynecology·D H Riddick, W F Kusmik
Jan 1, 1972·The Journal of Urology·R A Payne, R J Ryan
Apr 1, 1974·The Journal of Pathology·W B Robertson, B Warner
Apr 1, 1967·The Journal of Pathology and Bacteriology·J R TigheR C Curran
Oct 1, 1966·The Journal of Pathology and Bacteriology·A R CurrieC H Read
Jan 1, 1971·The Journal of Clinical Endocrinology and Metabolism·B D Weintraub, S W Rosen
Feb 1, 1972·Journal of Clinical Pathology·C W Elston, K D Bagshawe
Dec 1, 1974·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·P K Nakane, A Kawaoi
Jul 15, 1972·American Journal of Obstetrics and Gynecology·J L VaitukaitisG T Ross
Apr 1, 1971·Endocrinology·F J Morgan, R E Canfield
Aug 1, 1971·The Journal of Obstetrics and Gynaecology of the British Commonwealth·E S TeohW C Buhi
Oct 1, 1955·The Anatomical Record·G B WISLOCKI, E W DEMPSEY
Apr 1, 1960·The Journal of Obstetrics and Gynaecology of the British Empire·J D BOYD, W J HAMILTON

❮ Previous
Next ❯

Citations

Apr 21, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S Gosseye, F van der Veen
Aug 1, 1986·American Journal of Obstetrics and Gynecology·W B RobertsonJ Bonnar
Aug 1, 1986·Histopathology·N W WilsonE Heyderman
Apr 1, 1985·The British Journal of Dermatology·R M GrahamE Heyderman
Jun 1, 1991·Archives of Sexual Behavior·B Voeller
Oct 1, 1985·Archives of Sexual Behavior·J H Gagnon
Sep 1, 1993·The Journal of Experimental Zoology·L H Hoffman, F B Wooding
Oct 1, 1989·Histopathology·A C AndrewC H Buckley
Jan 10, 2020·Yeungnam University Journal of Medicine·Chulyong Park
Nov 1, 1988·Histopathology·M Wells, J N Bulmer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.