PMID: 7541029Mar 1, 1995Paper

Immunoreactive atrial and brain natriuretic peptides are co-localized in Purkinje fibres but not in the innervation of the bovine heart conduction system

The Histochemical Journal
M Hansson, S Forsgren

Abstract

Recently, we observed that atrial natriuretic peptide (ANP) immunoreactivity was present in Purkinje fibres and nerve fibre varicosities in the conduction system of the bovine heart. In order to elucidate further the morphological correlation between natriuretic peptides and the conduction system, the distribution of brain natriuretic peptide (BNP) was examined. The different parts of the conduction system in the bovine heart were dissected out and processed for immunohistochemistry with antisera against BNP and ANP. BNP immunoreactivity was frequently observed in Purkinje fibres of the atrioventricular bundle, whereas only a few Purkinje fibres in the ventricular part of the conduction system showed immunoreaction. BNP immunoreactivity was detected in regions of the Purkinje fibres which also showed ANP immunoreactivity. BNP immunoreactivity was not observed in nerve fibre varicosities. Methodologically, a larger number of small BNP immunofluorescent granular structures was observed by using an elution-restaining technique instead of conventional immunohistochemistry. The present study shows that BNP and ANP immunoreactivities frequently occur in the atrioventricular bundle and that they are co-localized in Purkinje fibres, bu...Continue Reading

References

Apr 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·G TramuJ Leonardelli
Jun 1, 1992·Chemical & Pharmaceutical Bulletin·Y HashimotoR Hori
Mar 1, 1992·International Journal of Cardiology·A PucciJ M Polak
Jan 1, 1991·Virchows Archiv. A, Pathological Anatomy and Histopathology·N MochizukiW W Hall
Jan 16, 1987·Cell·G Brawerman
Jun 1, 1989·Hypertension·M B Anand-SrivastavaM Cantin
Jan 16, 1989·Biochemical and Biophysical Research Communications·H ItohN Minamino
Jan 31, 1989·Biochemical and Biophysical Research Communications·Y SaitoN Minamino
Mar 31, 1989·Biochemical and Biophysical Research Communications·M KojimaH Matsuo
Dec 15, 1989·Biochemical and Biophysical Research Communications·M AburayaH Matsuo
Feb 28, 1989·European Journal of Pharmacology·W F OehlenschlagerM G Currie
Jan 1, 1985·Journal of Cardiovascular Pharmacology·J P MeheganS M McGuirk
Dec 15, 1989·Biochemical and Biophysical Research Communications·J J SeilhamerJ G Porter
Jan 1, 1986·Anatomy and Embryology·R P ThompsonM G Currie
Jun 1, 1987·Journal of Hypertension·R E LangD Ganten
Mar 3, 1988·Nature·T SudohH Matsuo
Jul 16, 1986·Biochemical and Biophysical Research Communications·M B Anand-Srivastava, M Cantin
Nov 30, 1988·Biochemical and Biophysical Research Communications·K MaekawaH Matsuo
Sep 15, 1988·Biochemical and Biophysical Research Communications·N MinaminoH Matsuo

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Citations

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Apr 26, 2007·International Urology and Nephrology·M Cagatay TaskapanHulya Taskapan
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Aug 25, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·B O LjungJ Fridén
Jul 12, 2011·Journal of Molecular and Cellular Cardiology·Andrew AtkinsonHalina Dobrzynski
Dec 14, 2004·Journal of Neuroimmunology·Solveig Persson-SjögrenSture Forsgren
Jul 16, 2013·Biochimica Et Biophysica Acta·Irina A Sergeeva, Vincent M Christoffels
Sep 21, 2011·PloS One·Emmelie BjörklundChristopher J Fowler
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May 23, 2000·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M WeiergräberT Schneider
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Sep 13, 2002·Microscopy Research and Technique·Magnus Hansson
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Apr 18, 1998·Circulation Research·A F MoormanW H Lamers
Aug 30, 2006·Reproductive Biology and Endocrinology : RB&E·Berith K TingakerSture Forsgren
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