PMID: 6106569May 1, 1980Paper

Immunoreactive plasma estrogens and vaginal hormone cytology in postmenopausal women

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
F Benjamin, S Deutsch

Abstract

The vaginal hormone cytology and the serum estrogen levels (as determined by radioimmunoassay) of 39 post-menopausal patients were compared. All cytologic parameters showed high statistical correlations with radioimmunoassay values, but these general associations could not be applied to individual patients. A more detailed analysis showed that an atrophic smear (eg, karyopyknotic index [KI], < 10%; parabasal level, > 20%; maturation value [MV], < 40%) indicate estrogen deficiency in the postmenopause. When the KI is 20%-40%, the parabasal cells less than 20% or the MV 40%-60%, the evaluation of estrogen status, on the basis of hormone cytology alone, is indeterminate. The three cytologic indices studied seem much more useful for detecting estrogen deficiency than estrogen excess in the postmenopause. The fact that immunochemical characteristics are not always related to biologic behavior must also be considered when interpreting these findings.

References

Jan 1, 1978·American Journal of Obstetrics and Gynecology·S Deutsch, F Benjamin
Nov 15, 1976·American Journal of Obstetrics and Gynecology·F Benjamin, S Deutsch
Aug 15, 1973·American Journal of Obstetrics and Gynecology·M D RaderG Mikhail
Jan 15, 1973·American Journal of Obstetrics and Gynecology·C H WuS G Lee
Jul 1, 1971·Steroids·C H Wu, L E Lundy
Jan 1, 1971·Journal of Reproduction and Fertility·G A DoveS F Lunn
Feb 1, 1966·The Journal of Obstetrics and Gynaecology of the British Commonwealth·J Frampton
Feb 16, 1957·Lancet·S YOUNGF C GREENWOOD
Apr 15, 1965·American Journal of Obstetrics and Gynecology·D CHARLESR A HARKNESS

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Citations

Jul 23, 2014·International Urogynecology Journal·M A WeberJ P W R Roovers
Jun 1, 1987·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·S DeutschA Frank

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