PMID: 8584216Oct 13, 1995Paper

Immunoreactivity for apolipoprotein A-IV in tanycytes and astrocytes of rat brain

Neuroscience Letters
K FukagawaP Tso

Abstract

Immunoperoxidase and immunofluorescence procedures were used to visualize polyclonal antiserum binding to apolipoprotein (apo) A-IV in rat brain. With both methods, tanycytes and astrocytes were labeled throughout both white and gray matter. Within the cells, the labeling was granular and it was confined to the perinuclear zone and proximal regions of the processes. The labeling was abolished by absorption of the primary antiserum with purified apo A-IV but not by absorption with apo E. These results suggest either that apo A-IV is synthesized by astrocytes, or that apolipoprotein that is synthesized in the small intestine or liver is selectively taken up and stored by the astrocytes.

References

Jan 1, 1991·The American Journal of Anatomy·D S KnightJ A Beal
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger

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Citations

Sep 1, 2005·Thyroid : Official Journal of the American Thyroid Association·Ronald M Lechan, Csaba Fekete
May 26, 2001·Annual Review of Nutrition·P TsoA B Thomson
May 26, 2004·Physiology & Behavior·Patrick Tso, Min Liu
Aug 22, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M LefevreF L Greenway
Jul 27, 1999·The Journal of Nutrition·P TsoT J Kalogeris
Nov 1, 1998·Journal of Gastroenterology and Hepatology·P TsoL Ee
Aug 10, 1999·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·A E RoherS Gracon
Mar 1, 1997·The Journal of Nutrition·T J KalogerisP Tso

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