Immunosorbents for LDL-apheresis

Biomaterials, Artificial Cells, and Artificial Organs
S N PokrovskyG F Benevolenskaya

Abstract

Low density lipoprotein (LDL) (1,03-1,05 g/ml) was utilized as antigen to obtain polyclonal (PcAb) and monoclonal (McAb) antibodies. Immunosorbents capable of selective removing LDL from human plasma were developed on the basis of the antibodies preparation. The sorbents called "Immunoliposorber PcAb" and "Immunoliposorber McAb" are currently undergoing clinical trials in the USSR Cardiology Research Center, Acad. of Med. Sciences.

Citations

Apr 7, 2007·Bulletin of Experimental Biology and Medicine·O I Afanas'evaS N Pokrovskii
Jan 7, 2005·Macromolecular Bioscience·Handan Yavuz, Adil Denizli
Jul 31, 2003·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Shinji Yokoyama
Jun 1, 1995·Artificial Organs·S N PokrovskyV V Kukharchuk
Jun 17, 2003·Journal of Biomaterials Science. Polymer Edition·Handan Yavuz, Adil Denizli
Nov 17, 2005·The International Journal of Artificial Organs·F MorelliM R Ruzzenenti

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