Immunosuppressant nonadherence in heart, liver, and lung transplant patients: associations with medication beliefs and illness perceptions

Transplantation
Mary KungElizabeth Broadbent

Abstract

Nonadherence to immunosuppressant medication is a significant problem among solid organ transplant recipients. Previous research suggests that patients' perceptions about their medications may be a better predictor of nonadherence than demographic factors. This study aimed to further investigate the role of patients' perceptions about their transplant and medication beliefs in nonadherence. This was a cross-sectional observational study. Participants were 87 heart, 46 lung, and 193 liver transplant patients. All surviving heart, lung, and liver transplant patients from Auckland City Hospital and Greenlane Hospital older than 16 years who had received their transplant at least 3 months before study commencement were mailed questionnaires. Standardized self-report measures were used to assess illness perceptions, medication beliefs, and adherence. Nonadherent patients had lower perceptions about the necessity of medication, weaker beliefs that medication could prevent rejection, and higher concerns about its harms, than adherers. Nonadherers perceived that their transplant and immunosuppressant medication caused more symptoms and were more distressed about symptoms than adherers; they understood their transplant less, perceived t...Continue Reading

References

Dec 31, 1997·Journal of Advanced Nursing·S P Wainwright, D Gould
Sep 25, 2002·Psychosomatic Medicine·Dana F KovalchickCarl A Brodkin
Dec 16, 2003·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Paolo CherubiniUgolino Livi
Oct 14, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Janet A ButlerJuan C Mason
Nov 13, 2004·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Fabienne DobbelsJohan Vanhaecke
Aug 17, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·David O TaylorMarshall I Hertz
Aug 27, 2005·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Marie A ChisholmLaura L Mulloy
Oct 4, 2005·Patient Education and Counseling·Marie A ChisholmLaura L Mulloy
May 9, 2006·Pediatric Transplantation·R K BerquistI F Litt
May 30, 2006·Journal of Psychosomatic Research·Elizabeth BroadbentJohn Weinman
Jun 15, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ronan E O'CarrollPeter C Hayes
Sep 12, 2007·Clinical Transplantation·Christiane KuglerMartin Strueber
Jan 24, 2008·Transplantation·Mary Amanda DewKenneth R McCurry
Jun 23, 2009·Journal of Psychosomatic Research·Elizabeth BroadbentKeith J Petrie
Apr 7, 2010·Journal of Evaluation in Clinical Practice·Scott E WilksMarie A Chisholm-Burns

❮ Previous
Next ❯

Citations

Feb 21, 2014·Current Opinion in Organ Transplantation·Annabel PriceMax Henderson
Nov 21, 2015·Transplantation·Bethany J FosterVicky Lee Ng
Nov 5, 2013·Transplantation Proceedings·O S Surman
Oct 23, 2012·Thoracic Surgery Clinics·Emily M RosenbergerRoger D Yusen
Feb 28, 2014·Journal of the American Association of Nurse Practitioners·Kathy J WheelerMary B Neiheisel
Sep 16, 2015·Journal of Evaluation in Clinical Practice·Kimberley CrawfordAllison Williams
Jul 17, 2015·Psychology & Health·Elizabeth BroadbentKeith J Petrie
Dec 7, 2013·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·James R RodrigueMichael P Curry
Apr 12, 2012·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·Sheila G JowseyChristopher G A McGregor
Jan 28, 2014·Psychology & Health·Vinayak Anand-KumarElizabeth Broadbent
Jul 19, 2016·Revista de calidad asistencial : organo de la Sociedad Española de Calidad Asistencial·G Costa-RequenaD Seron
Sep 16, 2014·Annales pharmaceutiques françaises·J-D BardetB Allenet
Nov 21, 2017·Journal of Korean Academy of Nursing·Mi Kyeong Jeon, Yeon Hwan Park
Oct 12, 2012·Digestive Diseases and Sciences·Sarah R Lieber, Michael L Volk
Oct 30, 2014·Current Heart Failure Reports·Erin E CoglianeseAlain L Heroux
Sep 16, 2021·Journal of Clinical Nursing·Ching-Hwa HsuShiow-Luan Tsay

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved