PMID: 11903386Mar 21, 2002Paper

Immunosuppressant side effect profile does not differ between organ transplant types

Clinical Transplantation
R P WinsettD K Hathaway

Abstract

Transplantation has enhanced the quality of life of all transplant recipients, but concern remains regarding the side effects of immunosuppressant drugs. In order to respond to these concerns, a survey to ascertain the side effect profile of transplant recipients was undertaken to identify the impact of chronic immunosuppression on quality of life. A nationwide survey of solid organ transplant recipients was carried out using a newly developed immunosuppressant side effect survey. Kidney, kidney-pancreas, liver and heart recipients responded to the survey (n = 505) and reflect the national distribution based on the UNOS data for organ type, recipient race and gender. The survey had four subscales: emotional burden, life/role responsibilities, mobility and GI distress. A fifth subscale included miscellaneous side effects that are more prevalent during the first 2 years post-transplant. Frequency and severity of each side effect were coded on a scale of 0-4 from 'no problem' to 'always' a problem. The entire range of possible scores (0-160) was reported, reflecting adequate variability in the responses. The sample consisted of 51% males, 77% Caucasians, 15% African Americans, with the remaining 8% other races. There were 225 (44....Continue Reading

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Citations

Sep 5, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·John T JosephRahul M Jindal
Sep 15, 2005·The Journal of Cardiovascular Nursing·Mary Amanda Dew, Andrea F DiMartini
Jan 22, 2009·Journal of Psychosomatic Research·Christiane KuglerKathleen Dracup
Apr 24, 2003·Clinical Transplantation·G V Ramesh PrasadJeffrey S Zaltzman
Aug 31, 2012·Journal of Health Psychology·Penelope StiefelChristiane Kugler
Dec 7, 2013·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·Yaprak S OrdinOzgül Vupa Cilengiroğlu
Jul 26, 2002·Pharmacoepidemiology and Drug Safety
Sep 12, 2007·Clinical Transplantation·Christiane KuglerMartin Strueber

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