Immunosuppression in canine renal allografts using niridazole

Transplantation
N SokucuJ Moran

Abstract

The immunosuppressive activity of niridazole in unmatched kidney allografts in nephrectomized dogs was studied. The drug alone was not effective, but improved survival when used with azathioprine and prednisolone or azathioprine alone. However, niridazole was toxic in dogs in the doses used (25 or 50 mg/kg/day).

Related Concepts

Metazoa
Azathioprine sodium
Canis familiaris
Graft Survival
Niridazole
Predonine
Transplantation, Homologous
Kidney Transplantation

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