Jan 1, 1976

Immunosuppressive role of the liver in the graft versus host reaction

Comptes rendus des séances de la Société de biologie et de ses filiales
D VuittonJ F Grenier


The ability of the liver to reduce the intensity of the graft versus host (GVH) reaction has been investigated in F1 hybrid rats implanted with parental lymph nodes. Intrahepatic and intrarenal tissue implantations were compared using classical GVH criteria. The intrahepatic implantation of lymph nodes suppress the mortality observed after intrarenal implantation. The results confirm the interest of portal drainage in organ transplantation and suggest a new site of implantation for lymphoid cells.

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Mentioned in this Paper

Graft-vs-Host Disease
Graft Vs Host Reaction
Lymph Nodes
Therapeutic Immunosuppression
SD Antigens

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