PMID: 7822668Jan 1, 1995Paper

Immunotherapy: a one-year prospective study to evaluate risk factors of systemic reactions

The Journal of Allergy and Clinical Immunology
D G TinkelmanJ Tunno

Abstract

We did a prospective study in Atlanta, Georgia, during 1991 on the rate of systemic reactions caused by immunotherapy in a clinic that uses aqueous allergen extracts. Immunotherapy reactions were monitored. Symptoms were recorded with respect to time of onset, involvement of respiratory tract or skin, and presence of hypotension. There were 98 systemic reactions in 96 patients (1 per 1600 visits or 1 per 47 patients). There was no direct relationship to seasonal pollen counts. There was, however, a correlation with the August to October increase in mold counts. There was no correlation between reactions and the age of the patient or the age of the extract. Patients were more likely to experience a reaction during the buildup phase than during maintenance therapy. The time of onset and the severity of the reaction were in agreement with previous reports. Severe reactions that included hypotension all occurred less than 30 minutes after the injection. In contrast to previous reports, patients with asthma were not at higher risk for a systemic reaction. Immunotherapy has a significant but low rate of systemic reaction. Potentially serious reactions may be mitigated by taking extra precautions during the earlier phases of an immuno...Continue Reading

References

Jul 1, 1976·The Journal of Allergy and Clinical Immunology·H L PenceH A Selfridge
May 1, 1992·The Journal of Allergy and Clinical Immunology·A HejjaouiJ Bousquet
Aug 1, 1988·The Journal of Allergy and Clinical Immunology·M A GreenbergR J Summers
Sep 18, 1967·JAMA : the Journal of the American Medical Association·W Franklin, F C Lowell
Feb 1, 1982·The Journal of Allergy and Clinical Immunology·T E Van MetreG L Rosenberg
Jan 1, 1980·Clinical Allergy·D VervloetJ Charpin

❮ Previous
Next ❯

Citations

Jun 1, 2000·Clinical Reviews in Allergy & Immunology·P A Greenberger
May 3, 2013·Current Allergy and Asthma Reports·Jennifer A Kannan, Tolly G Epstein
Oct 1, 2004·Allergologia et immunopathologia·A Iglesias-CadarsoA Pérez-Pimiento
Jul 30, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Giovanni PassalacquaGiorgio Walter Canonica
Nov 4, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·N AkçakayaH Cokuğraş
May 27, 2008·The Journal of Laryngology and Otology·J R Nichani, J de Carpentier
Apr 5, 2003·Immunopharmacology and Immunotoxicology·Eustachio NettisAlfredo Tursi
Jul 1, 1997·Allergy·E ToubiT D Golan
Jun 24, 1998·Allergy·B Rogala
Dec 18, 2009·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Linda S Cox
Jul 1, 2006·Treatments in Respiratory Medicine·Giovanni PassalacquaGiorgio Walter Canonica
Dec 13, 2012·American Journal of Rhinology & Allergy·Phil Lieberman
Mar 10, 2012·Immunotherapy·A Erika Morris, Gailen D Marshall
Mar 13, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Tolly G EpsteinDavid I Bernstein
Mar 13, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Matthew A Rank, David I Bernstein
Oct 16, 2015·International Forum of Allergy & Rhinology·Frederick M SchafferAndrew R Naples
Feb 26, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Hikmet Tekin NacarogluDemet Can
Jul 14, 2012·The Journal of Allergy and Clinical Immunology·Kuan-Wei ChenSusanne Vrtala
Apr 17, 2012·Oral and Maxillofacial Surgery Clinics of North America·Leslie Robin Halpern
Jan 5, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Christopher W CalabriaMichael S Tankersley
Nov 9, 2010·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Christopher M Webber, Christopher W Calabria
Mar 11, 2008·Otolaryngologic Clinics of North America·Bryan Leatherman
Oct 9, 2007·The Journal of Allergy and Clinical Immunology·Christopher W CalabriaMichael S Tankersley
Mar 6, 2007·The Journal of Allergy and Clinical Immunology·Harold S Nelson
Mar 27, 2009·Veterinary Dermatology·Christine Loewenstein, Ralf S Mueller
Dec 6, 2014·International Forum of Allergy & Rhinology·Frederick M SchafferLarry M Garner
Jun 3, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M SchiappoliG Passalacqua
Jul 15, 2015·The Journal of Allergy and Clinical Immunology·Marek JutelCezmi A Akdis
Apr 11, 2015·Immunopharmacology and Immunotoxicology·Ozgur KartalOsman Sener
Nov 14, 2013·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Giovanni Passalacqua
May 11, 2010·The Journal of Allergy and Clinical Immunology·Mark S La ShellJames M Quinn
Feb 13, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Deniz HanciCemal Cingi
Jun 29, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Peter S CreticosHendrik Nolte
Aug 19, 2007·Journal of Science and Medicine in Sport·John OrchardRichard Brown
Nov 4, 2008·Current Opinion in Allergy and Clinical Immunology·Hugh H Windom, Richard F Lockey
Oct 26, 2016·Allergologia et immunopathologia·M Tortajada-GirbésUNKNOWN Document of the Immunotherapy Working Group of the Spanish Society of Pediatric Clinical Immunology and Allergology (SEICAP)
Nov 1, 1995·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·B R Gordon
Aug 6, 2010·The Cochrane Database of Systematic Reviews·Michael J AbramsonJohn M Weiner
Mar 3, 2009·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Jaw-Ji TsaiMey-Fan Lee
Jan 1, 2013·Allergy & Rhinology·Julian MelamedAngela Ahuja-Malik
Nov 5, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·D S HurstD H Hunsaker
Mar 19, 2003·The Journal of Allergy and Clinical Immunology·Giorgio Walter Canonica, Giovanni Passalacqua
Dec 3, 2010·The Journal of Allergy and Clinical Immunology·Linda CoxDana Wallace

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Allergy and Clinical Immunology
G E Stewart, R F Lockey
The Journal of Allergy and Clinical Immunology
M J ReidT A Platts-Mills
The Journal of Allergy and Clinical Immunology
M A GreenbergR J Summers
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Tolly G EpsteinDavid I Bernstein
© 2022 Meta ULC. All rights reserved