PMID: 11905654Mar 22, 2002Paper

Immunotherapy for colorectal cancer: a challenge to clinical trial design

The Lancet Oncology
R Midgley, D Kerr

Abstract

Colorectal cancer is a leading cause of morbidity and mortality with about 18 000 deaths in the UK and 56 000 in the USA each year. Despite improvements in surgical technique, radiotherapy, and adjuvant chemotherapy, 50% of patients apparently 'cured' by surgery subsequently relapse and die of the disease. There is an obvious need to develop novel rational therapies based on understanding the molecular signatures that separate tumour from normal colorectal epithelium.

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Citations

May 15, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Xiaoming HuangPing Lan
Jan 5, 2002·Expert Opinion on Investigational Drugs·R Midgley, D Kerr
Nov 1, 2012·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·K Paige HardenJennifer L Tackett
Jan 22, 2014·The Journal of Nursing Education·Karee E Dunn
Feb 10, 2016·The British Journal of Educational Psychology·Kane Meissel, Christine M Rubie-Davies

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