Immunotherapy of neuroblastoma: present, past and future

Expert Review of Neurotherapeutics
L Raffaghello, Vito Pistoia

Abstract

Neuroblastoma is a neuroectodermal tumor of childhood with poor prognosis and low survival in patients with advanced-stage disease who respond to conventional therapies but unfortunately, often present relapse. Therefore, the search for novel therapeutic strategies is warranted and represents the objective of many investigators. Among the new, innovative approaches, immunotherapy has attracted much interest. However, until recently, little information was available about the immunogenicity of human neuroblastoma.

References

May 1, 1979·Radiology·R B Howman-GilesJ M Ash
Jan 3, 1990·Journal of the National Cancer Institute·J Folkman
Jul 1, 1995·Cancer Immunology, Immunotherapy : CII·M M Uttenreuther-FischerA L Yu
Jan 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J L MurrayR S Benjamin
Aug 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G M BrodeurF Hedborg
Dec 1, 1995·Cancer Immunology, Immunotherapy : CII·M M Uttenreuther-FischerA L Yu
Nov 15, 1997·Journal of the National Cancer Institute·H N LodeR A Reisfeld
Mar 28, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P E LovatC P Redfern
Jun 17, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A L YuF H Kung
Feb 2, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·H J NickersonJ Lukens
Dec 7, 2000·Medical and Pediatric Oncology·C PorembaB Dockhorn-Dworniczak
Dec 19, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R C SeegerK K Matthay
Aug 2, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R L SaylorsUNKNOWN Pediatric Oncology Group
Sep 11, 2001·Cancer·M S Lo PiccoloI Y Cheung
Nov 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B H KushnerN K Cheung
Mar 21, 2002·Nature Reviews. Cancer·L Altucci, H Gronemeyer
Apr 9, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D RibattiM Ponzoni
Jul 18, 2002·Nature Reviews. Drug Discovery·Jason Y Zhang
Jul 18, 2002·Nature Reviews. Drug Discovery·John C Reed
Aug 23, 2002·Epidemiology·Andrew F OlshanBrad H Pollock
Mar 4, 2003·Nature Reviews. Cancer·Garrett M Brodeur
Apr 11, 2003·Journal of Biomedicine & Biotechnology·Ettore BiagiMalcolm Brenner
May 30, 2003·The Oncologist·Joanna L WeinsteinSusan L Cohn
Jul 26, 2003·Cancer Letters·Simone Fulda, Klaus Michael Debatin
Oct 11, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Irene Y CheungNai-Kong V Cheung
Jan 22, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Brian H KushnerNai-Kong V Cheung
May 6, 2004·Pediatric Transplantation·C Patrick Reynolds
Jul 9, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·André OberthuerMatthias Fischer
Aug 18, 2004·Proceedings of the National Academy of Sciences of the United States of America·Roberta CastriconiCristina Bottino
Oct 16, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David M KingPaul Sondel

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Oncology : Official Journal of the European Society for Medical Oncology
H A LeitchJ M Connors
International Journal of Pancreatology : Official Journal of the International Association of Pancreatology
H OzakiK Mukai
Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses
J U Kelly
Clinical Oncology : a Journal of the Royal College of Radiologists
D D RosaG C Jayson
© 2022 Meta ULC. All rights reserved