Immunotherapy: when to initiate treatment in children

Allergy and Asthma Proceedings
Ira Finegold

Abstract

Although immunotherapy has documented short- and long-term benefits with regard to treatment of allergies and asthma as well as reducing development of new allergies and preventing progression of allergic rhinitis to asthma, the age to begin subcutaneous allergen immunotherapy appears established at the age of 5 years by published guidelines for treatment. The rationale for this age limit was examined and found to not reflect actual immunotherapy practice. Reasons for considering a downward revision are explored in this article. The conclusions from this review of past data and some recent studies with young children, especially with asthma, suggest that there is a need to consider beginning allergen immunotherapy earlier than the age of 5 years in more children.

Citations

Feb 13, 2013·Current Opinion in Allergy and Clinical Immunology·Alessandro FiocchiRichard W Weber
Oct 16, 2013·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Carlos E Baena-CagnaniUNKNOWN SLAAI Immunotherapy Working Group
Sep 25, 2010·Allergologia et immunopathologia·F Muñoz-López
Feb 13, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Deniz HanciCemal Cingi
Oct 26, 2016·Allergologia et immunopathologia·M Tortajada-GirbésUNKNOWN Document of the Immunotherapy Working Group of the Spanish Society of Pediatric Clinical Immunology and Allergology (SEICAP)
Mar 13, 2018·Clinical and Molecular Allergy : CMA·Matteo FerrandoGiorgio Walter Canonica
May 10, 2017·Frontiers in Pediatrics·Sophia TsabouriGeorge V Guibas
Dec 3, 2010·The Journal of Allergy and Clinical Immunology·Linda CoxDana Wallace
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