Impact of a gluten-free diet on bone mineral density in celiac patients

Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva
Lorete M S KotzeRenato Nisihara

Abstract

Osteoporosis (OP) is a metabolic bone illness that may complicate celiac disease (CD). It can lead to devastating consequences because of low bone mass and fragility fractures. To study the OP prevalence in a group of Brazilian patients with CD and the value of a gluten free diet (GFD). Retrospective study of celiac female patients from a single University Center followed with bone densitometries. Results from densitometry made at first visit were compared with a second study after a median time of 5 years. During this period, patients were submitted to a GFD according to orientations from special program training. Calcium and vitamin D were prescribed to those patients who did not reach the minimal daily requirement through diet. Forty-one celiac female patients, mean age 46.1 ± 14.8 years, were included. The prevalence of osteopenia at first visit was 56.1% and that of osteoporosis 29.2%. Osteoporosis was associated with longer disease duration (p = 0.01). The second densitometry was performed in a median time of 5 years (range 1 to 13 years) and disclosed 58.9% osteopenia and 28.2% osteoporosis. The GFD improved bone mass, mainly at (of) spine (comparison of T score with p = 0.03 and of bone mass in g/cm2 with p = 0.02), but...Continue Reading

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Citations

Sep 11, 2018·Endocrine Research·Marcella D WalkerMichael S Katz
Jul 20, 2019·Oxidative Medicine and Cellular Longevity·Francesca PalmacciMaura Palmery
Nov 5, 2019·Frontiers in Pediatrics·Aaron LernerTorsten Matthias

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