Impact of a program ensuring consistent response to acute drops in lung function in children with cystic fibrosis

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Michael S SchechterAndrea Molzhon

Abstract

Variation in CF pulmonary outcomes is multifactorial, but a significant component appears to be dependent upon differences in CF Center care. Previous investigations suggest that high performing CF centers are more consistent and proactive in the treatment of pulmonary exacerbations. We incorporated this approach into a program that could be bundled and shared with other CF Centers. The reorganization of CF pulmonary care at the Children's Hospital of Richmond included the development of a pulmonary algorithm to define a standard response to changes in lung function and run charts to track process and outcome measures. We calculated the rolling average of the best percent predicted FEV1 (ppFEV1) over the previous 12 months as our primary outcome measure. The mean of the best ppFEV1 in the previous 12 months rose from 87% predicted (65% predicted for those 13-18 years, 97% predicted for those 6-13 years) in January 2013 to 98% predicted (95% predicted for those 13-18 years, 110% predicted for those 6-13 years) in January 2018. The ppFEV1 difference between children 6-13 years and adolescents 13-18 years dropped from 34 to 14 during that time. Improvements in pulmonary outcomes can be accomplished rapidly using basic quality impr...Continue Reading

Citations

Jul 7, 2018·Pediatric Pulmonology·Michael S Schechter
Dec 10, 2019·Statistics in Medicine·Rhonda D SzczesniakJohn P Clancy
Jun 17, 2020·Expert Review of Respiratory Medicine·Claire J HoustonDamian G Downey
Jun 24, 2020·Pediatric Pulmonology·Jordana E HoppeElisabeth P Dellon
May 16, 2019·Pediatric Pulmonology·Stacey L MartinianoEdith T Zemanick
May 28, 2019·Pediatric Pulmonology·Adrienne P Savant, Susanna A McColley
Dec 17, 2020·JMIR Medical Informatics·Christopher WolfeCole Brokamp
Jul 2, 2019·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Don B SandersWayne J Morgan

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