Abstract
Survival of breast cancer patients depends on a number of factors which are not only prognostic but are also predictive. A number of studies have been carried out worldwide to find out prognostic and predictive significance of different clinicopathological and molecular variables in breast cancer. This study was carried out at Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, to find out the impact of different factors on overall survival of breast cancer patients coming from Northern Pakistan. This observational retrospective study was carried out in the Oncology Department of NORI Hospital. A total of 2,666 patients were included. Data were entered into SPSS 20. Multinomial logistic regression analysis was performed to determine associations of different variables with overall survival. P values <0.05 were considered significant. The mean age of the patients was 47.6 years, 49.5% being postmenopausal. Some 1,708 were ER positive and 1,615 were PR positive, while Her 2 neu oncogene positivity was found in 683. A total of 1,237 presented with skin involvement and 426 had chest wall involvement. Some 1,663 had > 5cm tumors. Lymph node involvement was detected in 2,131. Overall survival was less than 5 year...Continue Reading
References
Jan 1, 1989·Cancer·C L CarterD E Henson
Mar 1, 1993·Cancer·M K NairT Cherian
Feb 3, 1998·International Journal of Epidemiology·L MengL Wilkens
Jun 27, 2003·Journal of Surgical Oncology·Bekir KuruHaluk Alagol
Nov 6, 2003·Cancer·James S MichaelsonBarbara Smith
Nov 25, 2004·The Oncologist·Mary Cianfrocca, Lori J Goldstein
Sep 1, 2005·Cancer·Uwe GuthGad Singer
Sep 20, 2005·Breast Cancer Research : BCR·Nidal M Almasri, Mohammad Al Hamad
Aug 7, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A GoldhirschUNKNOWN 10th St. Gallen conference
Oct 24, 2008·World Journal of Surgical Oncology·Lobna AyadiTahya Boudawara
Oct 3, 2012·Breast Cancer Research : BCR·Ines Vaz-LuisNancy U Lin
Jan 16, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Abbas RezaianzadehAli Mousavizadeh
Jun 28, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Hafiz Muhammad AsifRiaz Ur Rehman
Aug 2, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Hee Jin ShimByung Joo Song
Aug 30, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Sema Sezgin GoksuHasan Senol Coskun
Dec 19, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Tohid Jafari-KoshkiFariborz Mokarian
Citations
Aug 13, 2015·Medicine·Taghipour Zahir ShokouhPoorya Barand
Jul 7, 2018·Drug Delivery and Translational Research·Sumayah Al-MahmoodTamara Minko
Sep 19, 2020·Curēus·Shahzada K SohailSamina Qamar
Dec 3, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Ahmad Reza BaghestaniParviz Shahmirzalou
Oct 3, 2018·The Breast Journal·Mojtaba MeshkatMohammad Esmaeil Akbari
Mar 20, 2021·Breast Cancer Research : BCR·Shih-Ying WuKounosuke Watabe
Sep 21, 2021·Women & Health·Shumaila MirajSadia Yasmeen
Dec 14, 2021·Frontiers in Oncology·Xiaoli HuChengcheng Li