Impact of ageing and soil contaminants on telomere length in the land snail

Ecotoxicology and Environmental Safety
Maxime LouzonAnnette de Vaufleury

Abstract

Telomeres (TLs) are non-coding DNA sequences that are usually shortened with ageing and/or chemical exposure. Bioindicators such as the land snail can be used to assess the environmental risk of contaminated soils. As for most invertebrates, the evolution of TLs with ageing or exposure to contaminants is unknown in this mollusc. The aims of this study were to explore the relationships between ageing, contaminant exposure, sublethal effects and TL length in the terrestrial gastropod Cantareus aspersus. TL length was investigated in haemocytes from five age classes of C. aspersus. The impact of contaminants on sub-adult snails exposed to Cd, Hg or a mixture of polycyclic aromatic hydrocarbons (PAHs) in soils for one or two months was studied. Bioaccumulation, growth, sexual maturity and TLs were measured. TL attrition was significant for the juvenile and sub-adult stages, but not later. Exposure to Cd increased the mortality (around 30%). Exposure to polluted soils inhibited growth (19-40%) and sexual maturity (6-100%). Although the health of the snails exposed to Cd, Hg and PAHs was altered, TL length in haemocytes was not disturbed, suggesting a high capacity of this snail species to maintain its TLs in haemocytes under chemica...Continue Reading

References

Apr 18, 1991·Nature·E H Blackburn
Aug 1, 1997·Archives of Environmental Contamination and Toxicology·A Gomot
Apr 11, 2000·Bulletin of Environmental Contamination and Toxicology·A Gomot-de Vaufleury, I Kerhoas
May 9, 2000·Mechanisms of Ageing and Development·M H Goyns, W L Lavery
May 12, 2000·Ecotoxicology and Environmental Safety·A Gomot-De Vaufleury
May 10, 2002·Nucleic Acids Research·Richard M Cawthon
Dec 18, 2002·Ecotoxicology and Environmental Safety·Michaël CoeurdassierPierre Marie Badot
Aug 13, 2004·Proceedings. Biological Sciences·Margaret E HallPat Monaghan
Apr 29, 2005·Micron : the International Research and Review Journal for Microscopy·Roberto VitturiMariastella Colomba
Mar 29, 2006·Environmental Toxicology and Chemistry·Renaud ScheiflerPierre-Marie Badot
Jul 13, 2006·Environmental Toxicology and Chemistry·Line Emilie SverdrupJohn Jensen
Oct 3, 2006·Environmental Geochemistry and Health·José Antonio MolinaPablo Higueras
Jan 20, 2007·Ecotoxicology·Laurent LagadicThierry Caquet
Jul 24, 2007·Ecotoxicology and Environmental Safety·Frédéric GimbertPierre-Marie Badot
Sep 17, 2009·Pflügers Archiv : European journal of physiology·Hisko OeseburgPim van der Harst
Jun 26, 2012·The Science of the Total Environment·B PaugetA de Vaufleury
Feb 28, 2013·Environmental and Molecular Mutagenesis·Dario AngelettiPasquale Mosesso
Jun 12, 2013·Cell·Carlos López-OtínGuido Kroemer
Jul 10, 2013·Proceedings of the National Academy of Sciences of the United States of America·Yuyu ChenHongbin Li
Jan 8, 2014·Experimental Gerontology·Heike GruberEva E R Philipp
May 13, 2014·Mechanisms of Ageing and Development·Charles SchumpertRekha C Patel
Apr 3, 2015·Methods in Ecology and Evolution·Daniel H NusseyPat Monaghan
May 12, 2015·PloS One·Charles SchumpertRekha C Patel
Jul 15, 2015·Journal of Hazardous Materials·Pierre-Emmanuel BaurandAnnette de Vaufleury
Oct 29, 2015·Environmental Science and Pollution Research International·Frédéric GimbertAnnette de Vaufleury
Nov 26, 2015·Developmental and Comparative Immunology·E A PilaP C Hanington
Apr 1, 2016·Cancer Discovery·Jerry W Shay
Feb 15, 2017·Indian Journal of Dermatology, Venereology and Leprology·Poonam PuriV Ramesh
Jun 2, 2017·Environmental Science and Pollution Research International·Gabrielle MagniezMarc Bonnard
Jul 15, 2017·General and Comparative Endocrinology·Frédéric AngelierOlivier Chastel
Aug 11, 2017·The Journal of Animal Ecology·Lewis G SpurginDavid S Richardson
Jan 18, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Hannah L Dugdale, David S Richardson

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Citations

Apr 12, 2021·Environmental Science and Pollution Research International·Maxime LouzonNicolas Capelli
Sep 1, 2021·Environmental Science and Pollution Research International·Romain ColpaertFrédéric Gimbert

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