Impact of alcohol-impregnated port protectors and needleless neutral pressure connectors on central line-associated bloodstream infections and contamination of blood cultures in an inpatient oncology unit

American Journal of Infection Control
Michael A SweetMehdi Hamadani

Abstract

A major risk factor for the development of bloodstream infection is the presence of a central venous catheter (CVC), especially in immunocompromised patients. CVC hub contamination is a risk factor for central line-associated bloodstream infection (CLABSI). This observational before-after trial in a tertiary care hospital's oncology unit included adult patients with a CVC. During the intervention period, the practice of central line hub care was changed from cleaning with alcohol wipes to using alcohol-impregnated port protectors. To accommodate the protectors, the needless hubs were changed to a neutral pressure connector. The intervention period (January-July 2010) was compared with a historical control (January-December 2009). A total of 3,005 central line-days and 1 CLABSI (a rate of 0.3 infections/1,000 central line-days) were documented during the intervention period, compared with 6,851 central line-days and 16 CLABSIs (2.3 infections/1,000 central line-days) during the control period (relative risk, 0.14; 95% confidence interval [CI], 0.02-1.07; P = .03). The rate of contaminated blood cultures (CBCs) from central lines was 2.5% (17 of 692) during the control period, but only 0.2% (1 of 470) during the intervention peri...Continue Reading

References

Jan 16, 1991·JAMA : the Journal of the American Medical Association·D W BatesT H Lee
Dec 4, 2002·American Journal of Infection Control·Naomi P O'gradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Jan 19, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Steve Z Menyhay, Dennis G Maki
May 10, 2008·Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses·Janet McMaster
Oct 25, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Alicia I HidronUNKNOWN Participating National Healthcare Safety Network Facilities
Dec 17, 2009·American Journal of Infection Control·Jonathan R EdwardsTeresa C Horan

❮ Previous
Next ❯

Citations

Feb 24, 2016·American Journal of Infection Control·Onno K HelderErwin Ista
Oct 23, 2012·American Journal of Infection Control·Marc-Oliver WrightLance R Peterson
Jun 11, 2015·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Julie M FlynnNicole C Gavin
Sep 24, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Mini KambojKent Sepkowitz
Oct 9, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jonas MarschallDeborah S Yokoe
Jun 16, 2015·Nursing Research and Practice·Nancy L Moureau, Julie Flynn
Dec 4, 2014·American Journal of Infection Control·Katreena Collette MerrillChristopher Macintosh
Jun 11, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jonas MarschallDeborah S Yokoe
May 7, 2016·Antimicrobial Resistance and Infection Control·Moi Lin LingChun-Ming Lee
May 18, 2016·American Journal of Infection Control·Susan A DolanAmelia Bumsted
Nov 7, 2016·Infectious Disease Clinics of North America·Mark E Rupp, Denisa Majorant
Jan 29, 2017·International Journal of Nursing Studies·Anne F Voor In 't HoltErwin Ista
Apr 30, 2016·British Journal of Nursing : BJN·Corinne Cameron-Watson
Jul 10, 2018·CA: a Cancer Journal for Clinicians·Ella J Ariza-Heredia, Roy F Chemaly
Feb 27, 2016·F1000Research·Edward J Septimus, Julia Moody
Mar 7, 2019·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Leonard A Mermel
Feb 24, 2018·Journal of the American Society of Nephrology : JASN·Steven M BrunelliDouglas P Killion
Oct 11, 2017·Journal of Infection Prevention·Evonne Curran
Jan 29, 2018·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·John M Boyce
Dec 31, 2019·Journal of the Pediatric Infectious Diseases Society·Emily R LevyW Charles Huskins
Aug 29, 2020·The Journal of Vascular Access·Deniz Taşdelen Öğülmen, Sebahat Ateş
Dec 30, 2014·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Anna CaseyTom Elliott
Jan 26, 2018·British Journal of Nursing : BJN·Anna L CaseyTom Sj Elliott
Aug 6, 2020·Applied Health Economics and Health Policy·Susan O'ConnellGrace Carolan-Rees
Jul 28, 2019·British Journal of Nursing : BJN·Andrew Barton
Oct 13, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Aaron M MilstoneUNKNOWN CCLIP Authorship Group
Sep 16, 2020·ACS Applied Materials & Interfaces·Joshua C DoverspikeMark E Meyerhoff

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Infection Control
Terri RebmannAssociation for Professionals in Infection Control and Epidemiology
Journal of Vascular Nursing : Official Publication of the Society for Peripheral Vascular Nursing
Jennifer Emuna, Debbie Kisner
© 2021 Meta ULC. All rights reserved