Impact of ankylosing spondylitis on sexual function: A systematic review and meta-analysis

Experimental and Therapeutic Medicine
Ya-Fei LiuSheng-Hao Tu

Abstract

A number of studies have reported the association of sexual problems with ankylosing spondylitis (AS); however, the results have been conflicting. The present study aimed to investigate the impact of AS on sexual function. To develop a more comprehensive understanding of sexual function in patients with AS, a systematic review and meta-analysis of the literature up to 2013 was conducted. Studies that assessed the impact of AS on sexual function by adopting the International Index of Erectile Function or the Female Sexual Function Index (FSFI) scoring system were included. Statistical analysis was performed using Review Manager statistical software (version 5.2). The weighted mean differences were calculated by employing a fixed or random effects model. A total of 484 cases from five studies were identified as being well-documented and included in the meta-analysis. Compared with healthy controls, male patients with AS have a significant reduction in sexual function scores of erectile function (-3.07), orgasmic function (-1.17), sexual drive (-0.72) and intercourse satisfaction (-1.89). Female patients with AS have a lower FSFI score in domains of desire (-0.34) and arousal (-0.87). In conclusion, AS has a certain impact on the ...Continue Reading

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Citations

Jun 5, 2018·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·İlknur Aykurt KarlıbelTekin Yıldız
Dec 3, 2015·The Journal of Rheumatology·Ya-Fei LiuSheng-Hao Tu
Apr 4, 2019·Arthritis Care & Research·Laura J RestouxAndrew M Briggs
Sep 1, 2018·Rheumatology International·Fernando Andres SommerfleckGustavo Citera
Jul 29, 2020·BMC Urology·Lauren Folgosa CooleyRobert E Brannigan
Apr 6, 2017·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Thiago SantanaRenato Nisihara
Apr 4, 2021·International Journal of Molecular Sciences·Katarzyna Romanowska-PróchnickaDariusz Szukiewicz

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