Impact of Aortic Insufficiency on Ascending Aortic Dilatation and Adverse Aortic Events After Isolated Aortic Valve Replacement in Patients With a Bicuspid Aortic Valve

The Annals of Thoracic Surgery
Yongshi WangXianhong Shu

Abstract

Aberrant flow pattern and congenital fragility bestows bicuspid aortic valve (BAV) with a propensity toward ascending aorta dilatation, aneurysm, and dissection. Whether isolated aortic valve replacement (AVR) can prevent further dilatation in BAV ascending aorta and what indicates concurrent aortic intervention in the case of valve operation remain controversial. From June 2006 to January 2009, patients with a BAV who underwent isolated AVR were consecutively included and categorized into aortic insufficiency (BAV-AI, n = 84) and aortic stenosis (n = 112) groups, and another population of patients with a tricuspid aortic valve with aortic insufficiency (n = 149) was also recruited during the same period for comparison of annual aortic dilatation rate and adverse aortic events after isolated AVR. With a median follow-up period of 72 months (interquartile range, 66 to 78 months), ascending aorta dilatation rates were faster in the BAV-AI group than the BAV plus aortic stenosis and tricuspid aortic valve with aortic insufficiency groups (both p < 0.001). The BAV-AI group showed a higher risk for adverse aortic events compared with both the BAV plus aortic stenosis (15.5% versus 4.5%; p = 0.008) and tricuspid aortic valve with aor...Continue Reading

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Citations

Apr 24, 2016·The Annals of Thoracic Surgery·Evaldas Girdauskas
Jun 14, 2015·The Annals of Thoracic Surgery·Anthony L EstreraHazim J Safi
Oct 12, 2016·International Journal of Cardiology·Luc CozijnsenBarbara J M Mulder
Mar 8, 2017·The Journal of Thoracic and Cardiovascular Surgery·Yan ShanXianhong Shu
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Feb 27, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Yongshi Wang, Boting Wu
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Sep 15, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Yan ShanXianhong Shu
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Mar 17, 2020·International Heart Journal·Yongshi WangXianhong Shu
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May 11, 2020·The Journal of Thoracic and Cardiovascular Surgery·Tatiana M Sequeira GrossEvaldas Girdauskas

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