Impact of arterial load on left ventricular diastolic function in patients undergoing cardiac catheterization for coronary artery disease

Circulation Journal : Official Journal of the Japanese Circulation Society
Hidekatsu FukutaGenjiro Kimura

Abstract

Although left ventricular (LV) diastolic dysfunction is associated with increased risk for incident heart failure in patients with coronary artery disease (CAD), no specific treatment for diastolic abnormalities has been established. Animal and small human studies have shown that an acute increase in LV afterload adversely impacts on LV early diastolic relaxation, but little is known about its chronic effect on diastolic function. The relationships of various components of arterial load (arterial compliance, total vascular resistance index, and augmentation index [AI] in the ascending aorta) with LV diastolic function indices determined on cardiac catheterization (relaxation time constant [Tau] and end-diastolic pressure [EDP]) and those on tissue Doppler echocardiography (early diastolic mitral annular velocity [E'] and the ratio of early diastolic mitral inflow to annular velocities [E/E']) were investigated in 303 consecutive patients undergoing cardiac catheterization for CAD. All components of arterial load correlated with diastolic function indices, with AI, an index reflecting late-systolic load, having the strongest correlations with diastolic function indices. After adjustment for potential confounders, AI correlated w...Continue Reading

References

Sep 1, 1976·The Journal of Clinical Investigation·J L WeissM L Weisfeldt
Sep 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·N B SchillerI Schnittger
May 1, 1985·The American Journal of Physiology·W J PaulusI Mirsky
Jan 1, 1972·Circulation Research·G D BuckbergJ I Hoffman
Oct 23, 1997·Journal of Cardiac Failure·D L Brutsaert, S U Sys
Mar 5, 1998·The American Journal of Physiology·D ChemlaY Lecarpentier
Sep 19, 1998·Japanese Circulation Journal·T IketaniC Ibukiyama
Oct 13, 1998·Journal of the American College of Cardiology·M J GarciaA L Klein
Apr 1, 1999·Journal of Hypertension·M F O'Rourke, G Mancia
Oct 28, 1999·Cardiovascular Research·A F Leite-MoreiraT C Gillebert
Mar 15, 2001·American Journal of Physiology. Heart and Circulatory Physiology·M YanoM Matsuzaki
Jun 27, 2002·Journal of the American College of Cardiology·Giuseppe SchillaciElmo Mannarino
Jun 21, 2003·Journal of Hypertension·Sarah A HopeJames D Cameron
Dec 1, 1958·Circulation·C B CHAPMANF J BONTE
May 7, 2004·The New England Journal of Medicine·Michael R ZileWilliam H Gaasch
Apr 8, 2006·Current Opinion in Cardiology·Dirk L Brutsaert, Gilles W De Keulenaer
Jul 21, 2006·The New England Journal of Medicine·Theophilus E OwanMargaret M Redfield
Oct 16, 2007·Journal of the American College of Cardiology·Barry A BorlaugDavid A Kass
Feb 6, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Kazuhiro YamamotoToshiaki Mano
Aug 1, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Miyuki Tsuchihashi-MakayaUNKNOWN JCARE-CARD Investigators
Sep 30, 2009·Journal of Cardiac Failure·Akshay S DesaiMark A Creager

❮ Previous
Next ❯

Citations

Jan 23, 2016·Current Heart Failure Reports·Julio A Chirinos, Payman Zamani
Dec 24, 2013·Journal of Cardiac Failure·Piercarlo BalloUNKNOWN Working Group Nucleus on Echocardiography of the Italian Society of Cardiology
Dec 26, 2015·Global Heart·Monica R Shah, Renee P Wong
Sep 25, 2012·Journal of the American College of Cardiology·Catherine N MartiJaved Butler
May 18, 2011·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Hirokazu MiyoshiTakashi Oki
Jun 28, 2018·European Heart Journal·Thomas Weber, Julio A Chirinos
Jul 30, 2014·Hypertension·Julio A ChirinosPatrick Segers
Feb 18, 2017·Journal of Cardiovascular Translational Research·Julio A Chirinos
Apr 13, 2017·Journal of Cardiovascular Translational Research·Julio A Chirinos
Nov 16, 2021·Physiology·Gary L PierceAnthony J Donato

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.