Impact of asthma medication and familial factors on the association between childhood asthma and attention-deficit/hyperactivity disorder: a combined twin- and register-based study: Epidemiology of Allergic Disease

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
K HolmbergC Almqvist

Abstract

Asthma and attention-deficit/hyperactivity disorder (ADHD) are prevalent in childhood and may cause functional impairment and stress in families. Previous research supports an association between asthma and ADHD in children, but several aspects of this relationship are unclear. Our aim was to study whether the association between asthma and ADHD is restricted to either the inattentive or the hyperactive/impulsive symptoms of ADHD, to explore the impact of asthma severity and asthma medication and the contribution of shared genetic and environmental risk factors on the asthma-ADHD relationship. Data on asthma, ADHD, zygosity and possible confounders were collected from parental questionnaires at 9 or 12 years on 20 072 twins through the Swedish Twin Register, linked to the Swedish Medical Birth Register, the National Patient Register and the Prescribed Drug Register. The association between asthma and ADHD, the impact of asthma severity and medication, was assessed by generalized estimating equations. Cross-twin-cross-trait correlations (CTCT) were estimated to explore the relative importance of genes and environment for the association. Asthmatic children had a higher risk of also having ADHD [odds ratio (OR) 1.53, 95% confiden...Continue Reading

References

Mar 1, 1995·The European Respiratory Journal·M I AsherA W Stewart
Jul 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·J BiedermanR Warburton
Aug 19, 1999·The Journal of Allergy and Clinical Immunology·M V White, N Sander
Jan 5, 2002·Journal of Developmental and Behavioral Pediatrics : JDBP·E L McQuaidJ H Nassau
Feb 28, 2002·Archives of Disease in Childhood·I HadjikoumiA D Milner
Sep 25, 2002·Journal of Internal Medicine·P LichtensteinN L Pedersen
Dec 9, 2004·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Jill S HaltermanPeter G Szilagyi
May 19, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C AlmqvistM Wickman
Jul 13, 2005·Journal of Attention Disorders·Paul HammernessJoseph Biederman
Jul 19, 2005·Lancet·Joseph Biederman, Stephen V Faraone
Jul 26, 2006·Journal of the American Academy of Child and Adolescent Psychiatry·Henrik LarssonJan-Olov Larsson
Jan 27, 2007·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Paul LichtensteinNancy L Pedersen
Apr 17, 2007·Journal of Developmental and Behavioral Pediatrics : JDBP·James A Blackman, Matthew J Gurka
Jun 2, 2007·The American Journal of Psychiatry·Guilherme PolanczykLuis Augusto Rohde
Mar 26, 2008·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Simon Francis ThomsenVibeke Backer
Apr 9, 2008·Archives of Pediatrics & Adolescent Medicine·Valerie SungDaryl Efron
May 1, 2008·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Lidy M J PelsserHuub F J Savelkoul
Sep 6, 2008·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Hasan YukselOzge Yilmaz
Feb 10, 2009·Families, Systems & Health : the Journal of Collaborative Family Healthcare·Elizabeth L McQuaidGregory K Fritz
Sep 30, 2009·Pediatrics·Anne Kristina OrtqvistCatarina Almqvist
Feb 18, 2010·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Sylvana C C RobbersAnja C Huizink
May 12, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C LundholmC Almqvist
Jun 25, 2010·Journal of Attention Disorders·Ole Bernt FasmerKetil J Oedegaard
Mar 1, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Hulya Ercan SaricobanMehmet Reha Cengizlier
Feb 13, 2013·Journal of Attention Disorders·Mu-Hong ChenYa-Mei Bai
Jun 12, 2013·Pharmacoepidemiology and Drug Safety·Anne K ÖrtqvistCatarina Almqvist
Oct 2, 2013·Indian Journal of Psychiatry·Vihang N Vahia
Feb 5, 2014·European Child & Adolescent Psychiatry·Annelies A J VerlaetHuub F J Savelkoul
Mar 13, 2014·BMC Psychiatry·Ho Jang KwonMyung Ho Lim
Sep 18, 2014·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Tong GongGöran Pershagen

❮ Previous
Next ❯

Citations

Jun 19, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jurjen van der SchansEelko Hak
Oct 30, 2016·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G RobertsJ A Woodfolk
Jan 24, 2017·Neuroscience and Biobehavioral Reviews·Jurjen van der SchansPieter J Hoekstra
May 2, 2017·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Adrienne P BorschukCynthia F Salorio
Jul 12, 2018·Pediatric Pulmonology·Tuğba Şişmanlar EyüboğluOğuz Köktürk
May 14, 2019·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Natalia BallardiniCarsten Flohr
Nov 17, 2019·International Journal of Behavioral Medicine·Anna CroghanKarin F Hoth
Jun 17, 2020·JAMA Network Open·Luyu XieSarah E Messiah
Aug 11, 2019·European Archives of Psychiatry and Clinical Neuroscience·Johanna WaltereitRobert Waltereit
Sep 24, 2020·Thorax·Emma Caffrey OsvaldCatarina Almqvist
Nov 23, 2016·Journal of Immunology Research·Isaac Melamed, Melinda Heffron
Apr 20, 2018·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Mindy K RossPeter G Szilagyi
Oct 25, 2016·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Emma Kristin JohanssonCarl-Fredrik Wahlgren
Apr 6, 2021·Psychological Medicine·Isabell BrikellJoanna Martin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.