Impact of blood transfusion on major infection after isolated coronary artery bypass surgery: Incidence and risk factors

Journal of the Saudi Heart Association
Shaikhah Awadh Al-HarbiAhmed A Arifi

Abstract

Cardiac surgery is considered one of the conditions that require a transfusion of blood and blood products in large amount. Infections are one of the most common complications after cardiac surgery. The aim of this study is to assess the impact of blood transfusion on major infections after isolated coronary artery bypass surgery (CABG). A retrospective cohort study was conducted at King Abdulaziz Cardiac Center. Eligible adult patients, aged >18 years, who underwent an isolated CABG from 2015 to 2016, were included. Patient demographic information, as well as pre-, intra-, and postoperative data were collected from the electronic hospital information system charts and perfusion records. For data analysis, categorical pre- and postoperative variables were summarized by frequencies and percentages, whereas for continuous variables, means and standard deviation or median and interquartile ranges were used. The sample size was 459 patients. Red blood cells (RBCs) were transfused in 60.1% of the patients, and the median number of units transfused per patient was 2. The mean hemoglobin threshold for transfusion was 8.2 (standard deviation ± 3.6) g/dL. The mean EuroSCORE of RBC recipients was 3.8 ± 5.9% and that of non-RBC recipients...Continue Reading

References

Jun 1, 1989·Transfusion·P I Tartter
Jan 1, 1995·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·A BlanchardH Sadeghi
Aug 1, 1994·Transfusion·E C Vamvakas, S B Moore
Nov 1, 1996·Transfusion·E C VamvakasP L Hibberd
Jul 2, 2002·The Journal of Thoracic and Cardiovascular Surgery·Margaret A OlsenVictoria J Fraser
Oct 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Margaret A OlsenVictoria J Fraser
May 25, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas R TalbotWilliam Schaffner
Oct 30, 2004·The Annals of Thoracic Surgery·Ziad A AliSteven Tsui
May 18, 2006·Emerging Infectious Diseases·Nicholas GravesMichael Whitby
Aug 20, 2010·Intensive Care Medicine·Patrick MöhnleUNKNOWN Multicenter Study of Perioperative Ischemia (McSPI) Research Group
Sep 30, 2010·The British Journal of Surgery·D J Leaper
Oct 4, 2011·Heart & Lung : the Journal of Critical Care·Lee Boon AngArlene Smaldone
Mar 28, 2013·Journal of Cardiothoracic Surgery·Filomena R B G GalasLudhmila A Hajjar
May 8, 2013·The Annals of Thoracic Surgery·Keith A HorvathEugene H Blackstone
May 28, 2013·The Annals of Thoracic Surgery·Bruce D Spiess
Jul 17, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Farrin A Manian

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

GraphPad Quick Cals
SPSS

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