Impact of body mass index and body weight variabilities on mortality: a nationwide cohort study

International Journal of Obesity : Journal of the International Association for the Study of Obesity
Ga Eun NamYong Gyu Park

Abstract

There is limited information regarding the impact of body mass index (BMI) and body weight (BWt) variabilities on mortality. This study aimed to investigate the association between BMI, BWt variabilities and subsequent mortality in the Korean population. This study used a representative sample cohort enrolled in the national health examination program conducted by the Korean National Health Insurance Service, and 125,391 individuals were included and followed up until 2013 (mean follow-up period = 84 months). BMI and BWt variabilities were estimated as the standard deviation (SD) and coefficient of variation (CV) of serial measurements of BMI and BWt (BMI_SD, BWt_SD, BMI_CV, and BWt_CV). Cox proportional hazard regression models were used to evaluate the all-cause and cause-specific mortality according to variability indices. Baseline BMI showed a non-linear association with all-cause mortality. The highest quartile (Q4) groups of variability indices were associated with increased all-cause mortality risk compared to the lowest quartile (Q1) groups after adjusting for confounding factors (hazard ratio [95% confidence interval] = 1.23 [1.11-1.37] for BMI_SD; 1.25 [1.06-1.47] for BMI_CV; 1.33 [1.20-1.48] for BWt_SD; 1.42 [1.28-1....Continue Reading

References

Jun 27, 1991·The New England Journal of Medicine·L LissnerK D Brownell
Sep 14, 1995·The New England Journal of Medicine·C IribarrenH Petrovitch
Oct 8, 1999·The New England Journal of Medicine·E E CalleC W Heath
Jan 22, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·K A PetersmarckM F Sowers
Aug 21, 2001·International Journal of Epidemiology·S G WannametheeM Walker
Dec 3, 2002·Archives of Internal Medicine·S Goya WannametheeMary Walker
Jun 4, 2004·Journal of the American Dietetic Association·Linda NebelingRachel Ballard-Barbash
Jan 12, 2005·Archives of Internal Medicine·Jeptha P CurtisHarlan M Krumholz
Mar 25, 2005·Journal of Internal Medicine·W B DrøyvoldUNKNOWN Nord-Trøndelag Health Study
Apr 26, 2005·Journal of Community Health·Vanessa A DiazCharles J Everett
Aug 24, 2006·The New England Journal of Medicine·Kenneth F AdamsMichael F Leitzmann
Aug 24, 2006·The New England Journal of Medicine·Sun Ha JeeJonathan M Samet
Nov 30, 2006·Nutrition Reviews·Tina Berentzen, Thorkild I A Sørensen
Jun 1, 2007·Journal of the American Geriatrics Society·Yutaka TakataTadamichi Takehara
Aug 7, 2007·European Journal of Epidemiology·Peter RzehakJoachim Heinrich
Nov 23, 2007·Journal of the American Geriatrics Society·Paula DiehrGregory Burke
Apr 5, 2008·International Journal of Epidemiology·Catherine SauvagetRengaswamy Sankaranarayanan
Feb 19, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T ShimazuI Tsuji
Apr 24, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Alice M ArnoldStephen Kritchevsky
May 13, 2009·Archives of Internal Medicine·Alison E FieldWalter C Willett
Jun 27, 2009·Nutrition Research Reviews·Mary HarringtonRichard C Cottrell
Nov 18, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A NanriUNKNOWN Japan Public Health Center- based Prospective Study Group
Feb 8, 2011·Lancet·Mariel M FinucaneUNKNOWN Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index)
Jan 31, 2012·American Journal of Epidemiology·Victoria L StevensSusan M Gapstur
Jan 3, 2013·JAMA : the Journal of the American Medical Association·Katherine M FlegalBarry I Graubard
Aug 2, 2013·Diabetes Care·Vojtech Hainer, Irena Aldhoon-Hainerová
Sep 30, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·T MehtaK Casazza
Nov 17, 2015·Journal of Nutrition in Gerontology and Geriatrics·Feon W ChengGordon L Jensen

❮ Previous
Next ❯

Citations

Nov 21, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·M KimJ H Lee
Jul 3, 2019·Journal of Clinical Medicine·Kye-Yeung ParkYong-Gyu Park

❮ Previous
Next ❯

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.