Impact of body mass index in Korean patients with renal cell carcinoma

Cancer Causes & Control : CCC
Hyun Hwan SungHan-Yong Choi

Abstract

The aim of the current study was to examine the impact of preoperative body mass index (BMI) in Korean patients with surgically treated renal cell carcinoma (RCC). From 1994 to 2008, a total of 1,487 patients underwent nephrectomy for RCC. All patients were classified into three groups according to Asian BMI classification by Asia Cohort Consortium: <18.5, 18.5 to <25, and 25 kg/m(2) or greater group, which represents the underweight (n = 42, 2.8%), normal (n = 833, 56.0%), and obesity (n = 612, 41.2%) group, respectively. Survival analyses and predictive factors for cancer-specific survival among the three groups were evaluated. Subgroup survival analysis of organ-confined and advanced disease was performed. An overall median follow-up was 54.8 months. Mean ± SE estimated cancer-specific survival in all patients at 5 and 10 years was 88.0 ± 1.0% and 81.4 ± 1.4%, respectively. In the multivariate model after adjusting preoperative and postoperative variables, the underweight group had a significantly worse prognosis than the normal group (hazard ratio (HR): 2.17, 95% confidence interval (95% CI): 1.16-4.08, p = 0.016), meanwhile the obesity group was associated with improved survival (HR: 0.66, 95% CI: 0.45-0.96, p = 0.032). In...Continue Reading

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Citations

Oct 12, 2018·Asia-Pacific Journal of Clinical Oncology·Hyun Cheol JeongSung-Hoo Hong
Sep 27, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Zhigang XueCharlene Compher
Oct 1, 2016·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M BagheriK Djafarian
Oct 24, 2017·Current Opinion in Urology·Rana TahbazAxel S Merseburger
Nov 6, 2012·Current Opinion in Supportive and Palliative Care

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