Impact of body mass index on postoperative complications and long-term survival in patients with esophageal squamous cell cancer

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
K KamachiH Makuuchi

Abstract

Undernutrition and cachexia have been suggested to be risk factors for postoperative complications and survival in cancer patients. The aim of this study was to investigate whether body mass index (BMI) is related to the short-term and long-term outcomes in patients who undergo an esophagectomy for the resection of esophageal squamous cell cancer (ESCC). Three hundred forty patients who underwent an esophagectomy for the resection of ESCC between 2003 and 2008 were retrospectively reviewed. The patients were divided into two groups: an L-BMI group characterized by a BMI < 18.5 kg/m(2) and an N-BMI group characterized by a BMI ≥ 18.5 kg/m(2). Clinical and pathological outcome were compared between groups. The study included 40 patients in the L-BMI group and 300 patients in the N-BMI group. A clinicopathological assessment showed that nodal involvement was seen more frequently in the L-BMI group (P = 0.016). Pulmonary complications seemed to occur more frequently in the L-BMI group (P = 0.006). The 5-year overall survival rate was higher in the N-BMI group (63.6%) than in the L-BMI group (32.3%) (P < 0.001). The 5-year disease-free survival rate was also higher in the N-BMI group (58.0%) than in the L-BMI group (33.6%) (P = 0.00...Continue Reading

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Citations

Apr 12, 2016·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Kirsten LindnerRichard Hummel
Jan 4, 2017·Interactive Cardiovascular and Thoracic Surgery·Ryu KanzakiMeinoshin Okumura
May 13, 2018·World Journal of Surgical Oncology·Cui WangGongchao Wang
Jan 21, 2020·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Sivesh K KamarajahEwen A Griffiths
Sep 27, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Zhigang XueCharlene Compher
Jun 5, 2018·Annals of Gastroenterological Surgery·Motonari RiYasuyuki Seto
May 26, 2020·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Sivesh K KamarajahEwen A Griffiths
Jul 14, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Kotaro SugawaraYasuyuki Seto

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