Impact of body mass index on pulmonary complications in patients with non-Hodgkin lymphoma treated with hematopoietic stem cell transplant

Leukemia & Lymphoma
Chi LinFausto R Loberiza

Abstract

The objective of this study was to examine the association between body mass index (BMI) and the incidence of pulmonary complications (PCs) after hematopoietic stem cell transplant (HCT). We reviewed 398 adult patients with non-Hodgkin lymphoma (NHL) who received autologous or allogeneic HCT between 1993 and 1997. BMI was classified as normal (18.5 < BMI ≤ 24.9), overweight (24.9 < BMI ≤ 30) and obese (BMI > 30). Multivariate logistic regression was used to analyze the relationship between BMI and presence of PCs within 100 days post-HCT while adjusting for patient-, disease- and transplant-related variables. The incidence of PCs within 100 days post-HCT was 32% (n = 129). Median BMI was 25.4 (range: 18.6-52.2). Median age was 48.8 years (range: 19.5-73.6 years). Multivariate analysis failed to show significant association between BMI and PCs. However, a total body irradiation (TBI)-based conditioning regimen was associated with lower rate of PCs.

References

Jan 1, 1990·Mayo Clinic Proceedings·M J KrowkaH C Hoagland
Feb 1, 1986·Annals of Internal Medicine·R S WeinerA A Rimm
Nov 1, 1993·Respiratory Medicine·R BreuerR Or
Apr 1, 1996·Chest·A O SoubaniP M Hassoun
Feb 13, 2001·International Journal of Radiation Oncology, Biology, Physics·O ThomasJ Cuillière
Sep 26, 2001·Bone Marrow Transplantation·G MeloniF Mandelli
Mar 10, 2004·International Journal of Hematology·Jeeyun LeeKeunchil Park
Apr 26, 2006·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Willis H NavarroJ Douglas Rizzo
Oct 28, 2006·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Navneet S MajhailDaniel J Weisdorf
Jan 13, 2009·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Shigeo FujiUNKNOWN Japan Marrow Donor Program
Apr 24, 2010·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Willis H NavarroJ Douglas Rizzo
Sep 8, 2010·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Collin C BarkerUNKNOWN Regimen-Related Toxicity Writing Committee, Center for International Blood and Marrow Transplant Research
Nov 3, 2010·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Mark CrowtherDominic J Culligan
Sep 10, 2011·Journal of Radiation Research·Hiromi IzawaKeisuke Sasai
Dec 14, 2011·Clinical Transplantation·Manuela Aguilar-GuisadoUNKNOWN Spanish Network for Research in Infectious Diseases
Aug 16, 2012·European Journal of Clinical Nutrition·M WhiteP S W Davies

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