Impact of changes of positive end-expiratory pressure on functional residual capacity at low tidal volume ventilation during general anesthesia.

Journal of Anesthesia
Daizoh SatohKei Nagaya

Abstract

Several reports in the literature have described the effects of positive end-expiratory pressure (PEEP) level upon functional residual capacity (FRC) in ventilated patients during general anesthesia. This study compares FRC in mechanically low tidal volume ventilation with different PEEP levels during upper abdominal surgery. Before induction of anesthesia (awake) for nine patients with upper abdominal surgery, a tight-seal facemask was applied with 2 cmH(2)O pressure support ventilation and 100 % O(2) during FRC measurements conducted on patients in a supine position. After tracheal intubation, lungs were ventilated with bilevel airway pressure with a volume guarantee (7 ml/kg predicted body weight) and with an inspired oxygen fraction (FIO(2)) of 0.4. PEEP levels of 0, 5, and 10 cmH(2)O were used. Each level of 5 and 10 cmH(2)O PEEP was maintained for 2 h. FRC was measured at each PEEP level. FRC awake was significantly higher than that at PEEP 0 cmH(2)O (P < 0.01). FRC at PEEP 0 cmH(2)O was significantly lower than that at 10 cmH(2)O (P < 0.01). PaO(2)/FIO(2) awake was significantly higher than that for PEEP 0 cmH(2)O (P < 0.01). PaO(2)/FIO(2) at PEEP 0 cmH(2)O was significantly lower than that for PEEP 5 cmH(2)O or PEEP 10 ...Continue Reading

References

Apr 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R W Wahba
Apr 1, 1988·British Journal of Anaesthesia·G DamiaL Tarenzi
Jul 1, 1974·British Journal of Anaesthesia·A M HewlettJ S Milledge
Nov 1, 1996·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R M Wahba
May 26, 2007·Anesthesiology·Marcus J SchultzOgnjen Gajic
Nov 16, 2007·Journal of Clinical Monitoring and Computing·Gary ChoncholasErkki Heinonen
Jan 9, 2010·Critical Care : the Official Journal of the Critical Care Forum·Rogier M DetermannMarcus J Schultz
Sep 9, 2010·The Cochrane Database of Systematic Reviews·Georgina ImbergerAnn Merete Møller

❮ Previous
Next ❯

Citations

Jun 22, 2014·Journal of the Chinese Medical Association : JCMA·Elif Dogan BakiNilgun Kavrut Ozturk
Nov 12, 2015·Indian Journal of Anaesthesia·Vijay Saraswat
Dec 3, 2014·Lancet·Sabrine N T HemmesMarcus J Schultz
Jun 21, 2017·Anesthesia and Analgesia·Davide D'AntiniUNKNOWN European Society of Anaesthesiology and the PROtective VEntilation Network
Sep 18, 2018·Anesthesia and Analgesia·Maximilian S SchaeferTanja Astrid Meyer-Treschan

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary artery bypass

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.