Impact of Chromatin on HIV Replication

Genes
Luis M AgostoAndrew J Henderson

Abstract

Chromatin influences Human Immunodeficiency Virus (HIV) integration and replication. This review highlights critical host factors that influence chromatin structure and organization and that also impact HIV integration, transcriptional regulation and latency. Furthermore, recent attempts to target chromatin associated factors to reduce the HIV proviral load are discussed.

References

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Citations

Jun 6, 2018·AIDS Research and Human Retroviruses·Luis M Agosto, Andrew J Henderson
May 23, 2019·PLoS Pathogens·Matthew GagneAndrew J Henderson
Jun 29, 2017·PloS One·Jason D GraciAndrew J Henderson
Apr 11, 2021·Proceedings of the National Academy of Sciences of the United States of America·Kyle D PedroAndrew J Henderson

Methods Mentioned

BETA
nuclear translocation
acetylation
ChIP
PCR

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