Impact of chronic kidney disease on mortality: A nationwide cohort study

Kidney Research and Clinical Practice
Kyeong Min KimDong-Ryeol Ryu

Abstract

Mortality is higher in patients with chronic kidney disease (CKD) than in the general population, but little information is available on CKD-related mortality that is representative of the Korean population. Our objective was to investigate mortality risk in Korean patients with CKD. We identified patients with incident CKD who had not undergone dialysis or kidney transplantation between January 1, 2003 and December 31, 2007 in Korea using the database of the Korean National Health Insurance Service-National Sample Cohort, and stratified the population into the following three groups: group 1 (n = 1,473), controls; group 2 (n = 2,212), patients with diabetes or hypertension, but without CKD; and group 3 (n = 2,212), patients with CKD. We then monitored them for all-cause mortality until December 2013. A total of 1,473 patients were included in this analysis. During the follow-up period, 941 patients in group 3 died (134 deaths/1,000 person-years) compared with 550 deaths in the group 2 (34 deaths/1,000 person-years) and 459 deaths in group 1 (30 deaths/1,000 person-years). The rate ratio for mortality rate was 4.5, and the hazard ratio for mortality was 4.88 (95% confidence interval [CI], 4.36-5.47, P < 0.001) in patients in gr...Continue Reading

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Citations

Jan 19, 2020·International Journal of Environmental Research and Public Health·Jiyun Jung Clinical Research Center For End-Stage Renal Disease Crc For Esrd Investigators
Jul 7, 2020·Clinical Journal of the American Society of Nephrology : CJASN·Jeonghwan LeeJung Pyo Lee
Aug 8, 2020·Journal of the American Society of Nephrology : JASN·Young Su JooSeung Hyeok Han
Sep 3, 2020·The Korean Journal of Internal Medicine·So Mi Kim, Il Han Song
Jan 15, 2021·Scientific Reports·Hyunjin RyuUNKNOWN Representing KNOW-CKD Study Group
Aug 6, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Young Su JooJung Tak Park
Sep 15, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jinkwon KimKyung-Yul Lee
Mar 16, 2021·American Journal of Physiology. Renal Physiology·Jung Nam AnSeung Hee Yang
May 1, 2021·International Journal of Environmental Research and Public Health·Seo Yun HwangSang Min Park
Jun 3, 2021·International Journal of Environmental Research and Public Health·Patricia Bonilla-SierraJosé Rafael González-López
Jun 22, 2021·The Korean Journal of Internal Medicine·Jee Young Lee, Seung Hyeok Han

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