Impact of chronic obstructive pulmonary disease exacerbations on patients and payers

Proceedings of the American Thoracic Society
J A Wedzicha, Tom Wilkinson

Abstract

Chronic obstructive pulmonary disease (COPD) is not only an established major cause of mortality and morbidity but is increasing in worldwide prevalence despite current medical interventions. The natural history of COPD is punctuated by periods of acute symptomatic, physiologic, and functional deterioration or exacerbations. These events are responsible for considerable additional morbidity and mortality and impact on patients' long-term health status. Despite advances in understanding disease mechanisms and in treatment, exacerbations continue to be the major cause of COPD-associated hospitalization, and provision for their management incurs considerable health care costs. Although pharmacologic therapies may improve clinical outcomes, these benefits must be optimized by prompt diagnosis and delivery. This will require improved understanding of this complex disease by physicians and patients alike.

Citations

Aug 21, 2008·American Journal of Respiratory and Critical Care Medicine·Antonello PunturieriJames P Kiley
Jan 1, 2011·Multidisciplinary Respiratory Medicine·Anna Maria MorettiCinzia Germinario
Oct 2, 2014·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Parameswaran NairJohn D Brennan
Dec 3, 2014·La Presse médicale·François ChabotAri Chaouat
Jul 4, 2007·Respiratory Medicine·Liesel D'silvaKrishnan Parameswaran
Dec 18, 2010·Journal of Telemedicine and Telecare·Nabil A Jarad, Zoe M Sund
May 19, 2018·Expert Review of Respiratory Medicine·Edward Kerwin, Gary T Ferguson
Jan 23, 2018·American Journal of Respiratory and Critical Care Medicine·James D ChalmersMelissa J McDonnell
Feb 2, 2017·European Respiratory Review : an Official Journal of the European Respiratory Society·Alexander G MathioudakisJørgen Vestbo
Mar 22, 2018·American Journal of Therapeutics·Eric DietrichKyle A Davis
May 6, 2015·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Allison A LambertM Bradley Drummond
Jul 16, 2020·Therapeutic Advances in Respiratory Disease·Aishath Fazleen, Tom Wilkinson
May 19, 2010·Expert Review of Respiratory Medicine·Sally Spencer
May 31, 2016·The Clinical Respiratory Journal·Hulya SahinAyse Ozsoz
Apr 21, 2018·Chronic Respiratory Disease·Hulya Sahin, Ilknur Naz
May 19, 2020·ERJ Open Research·Chia Wei Kong, Tom M A Wilkinson
Jul 28, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jennifer Alison
Feb 6, 2021·NPJ Primary Care Respiratory Medicine·Danielle RoseTom M A Wilkinson
Feb 13, 2021·NPJ Primary Care Respiratory Medicine·Emma RayTom M A Wilkinson
Mar 23, 2021·The Clinical Respiratory Journal·Clair BarberPeter H Howarth
Aug 21, 2021·European Respiratory Review : an Official Journal of the European Respiratory Society·H Burke, T M A Wilkinson
Aug 24, 2021·Frontiers in Cellular and Infection Microbiology·Jake R WeeksTom M A Wilkinson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.