Impact of current smoking and alcohol consumption on gastrostomy duration in patients with head and neck cancer undergoing definitive chemoradiotherapy

JAMA Otolaryngology-- Head & Neck Surgery
Ross O'SheaPatrick Sheahan

Abstract

Prophylactic gastrostomy tube (GT) insertion prior to chemoradiotherapy is a valuable nutritional adjunct in patients with head and neck cancer undergoing nonsurgical treatment. However, concerns have been expressed regarding high rates of GT dependence. There is little information in the literature regarding the impact of modifiable risk factors such as smoking and alcohol consumption on duration of GT use and dependence rates. To study the duration of GT use in patients with head and neck cancer at our institution and to investigate risk factors for prolonged GT duration and dependence, including the impact of smoking and alcohol consumption. This retrospective study at an academic teaching hospital included 104 patients with squamous cell carcinoma of the head and neck undergoing definitive treatment with either chemoradiotherapy (n = 84) or radiotherapy alone (n = 20). Prophylactic GT insertion prior to commencement of treatment. Duration of GT use after completion of chemoradiotherapy or radiotherapy and the impact of risk factors on same. Duration of GT use was analyzed using Kaplan-Meier survival curves, with censoring of patients who developed cancer recurrence or died. The median duration of GT use was 9 months. The ac...Continue Reading

Citations

Feb 15, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ulrike SchillerOrlando Guntinas-Lichius
Apr 21, 2016·Clinical Oncology : a Journal of the Royal College of Radiologists·R Simcock, R Simo
Nov 8, 2017·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Noelle K LoConteAnthony J Alberg
Aug 14, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Ana Raquel MonteiroMaria Margarida Teixeira
Dec 31, 2020·Nutrients·Adam BrewczyńskiTomasz Rutkowski

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