Impact of Diabetes and Increasing Body Mass Index Category on Left Ventricular Systolic and Diastolic Function

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Arnold C T NgJeroen J Bax

Abstract

Diabetes and obesity are both worldwide growing epidemics, and both are independently associated with increased risk for heart failure and death. The aim of this study was to examine the additive detrimental effect of both diabetes and increasing body mass index (BMI) category on left ventricular (LV) myocardial systolic and diastolic function. The present retrospective multicenter study included 653 patients (337 with type 2 diabetes and 316 without diabetes) of increasing BMI category. All patients had normal LV ejection fractions. LV myocardial systolic (peak systolic global longitudinal strain and peak systolic global longitudinal strain rate) and diastolic (average mitral annular e' velocity and early diastolic global longitudinal strain rate) function was quantified using echocardiography. Increasing BMI category was associated with progressively more impaired LV myocardial function in patients with diabetes (P < .001). Patients with diabetes had significantly more impaired LV myocardial function for all BMI categories compared with those without diabetes (P < .001). On multivariate analysis, both diabetes and obesity were independently associated with an additive detrimental effect on LV myocardial systolic and diastolic...Continue Reading

Citations

Feb 14, 2019·Revista da Associação Médica Brasileira·José Carlos de Lima JúniorAndrei C Sposito
Dec 18, 2018·The International Journal of Cardiovascular Imaging·Amiliana M SoesantoManoefris Kasim
Sep 20, 2019·Diagnostics·Elena-Daniela GrigorescuLaurentiu Sorodoc
Jun 9, 2020·The International Journal of Cardiovascular Imaging·Kristoffer Grundtvig SkaarupTor Biering-Sørensen
Feb 4, 2021·EClinicalMedicine·M A de GraafA H E Roukens
Nov 15, 2020·Nature Reviews. Cardiology·Arnold C T NgJeroen J Bax
Aug 27, 2018·Trends in Endocrinology and Metabolism : TEM·Jun RenYingmei Zhang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Roger E PeverillLesley Donelan
Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Marcia M BarbosaMaria Pereira Nunes
© 2022 Meta ULC. All rights reserved