Impact of different nasal masks on CPAP therapy for obstructive sleep apnea: a randomized comparative trial

The Clinical Respiratory Journal
Pierre-Charles Neuzeret, Laurent Morin

Abstract

Patient interface is important for the success of continuous positive airway pressure (CPAP), but few trials have examined the influence of mask choice on CPAP adherence. To compare the impact of different nasal masks on CPAP in patients with newly-diagnosed obstructive sleep apnea (OSA). OSA patients were randomized in a 2:3 ratio to receive CPAP via different first-line nasal masks: ResMed Mirage FX® (MFX) or control mask (Fisher & Paykel Zest® , HC407® or Philips EasyLife® ). Mask acceptance, CPAP compliance and Home Care Provider (HCP) interventions were compared between groups after 3 months of CPAP therapy using modified intent-to-treat (mITT; after exclusion of patients with mouth leaks during CPAP initiation) and on-treatment (OT; CPAP adherent) analyses. Of 285 randomized patients, 90 requiring a full-face mask were excluded, leaving 195 and 151 in the mITT and OT analyses, respectively. Mask acceptance rate was higher in the MFX versus control group (mITT: 79% vs 68%, P = 0.067; OT: 90% vs 76%, P = 0.022). CPAP compliance was higher (5.9 ± 1.8 vs 5.1 ± 1.6 h/night, P = 0.011) and nasal mask issue-related HCP visits lower (3% vs 17%, P = 0.006) in the MFX group. Nasal mask failures due to mask discomfort (5% vs 1%) or ...Continue Reading

References

Jul 1, 1996·American Journal of Respiratory and Critical Care Medicine·G N RichardsC E Sullivan
May 1, 1997·Health Affairs·A C Enthoven, C B Vorhaus
Sep 19, 1998·Thorax·I L MortimoreN J Douglas
Feb 2, 1999·American Journal of Respiratory and Critical Care Medicine·H M EnglemanN J Douglas
Apr 8, 1999·American Journal of Respiratory and Critical Care Medicine·C J HoyN J Douglas
Nov 4, 2000·Nature Genetics·J H Petrini
Mar 19, 2002·American Journal of Respiratory and Critical Care Medicine·Maree BarnesRobert J Pierce
Aug 16, 2005·Chest·Francisco Campos-RodriguezAna Fernandez-Palacin
Oct 29, 2005·Patient Education and Counseling·Alain GolayThierry Rochat
Nov 8, 2005·Sleep & Breathing = Schlaf & Atmung·Dale CollerSairam Parthasarathy
Oct 21, 2006·Current Opinion in Pulmonary Medicine·Terri E Weaver
Oct 21, 2006·The Cochrane Database of Systematic Reviews·C L ChaiB Smith
Feb 6, 2008·Proceedings of the American Thoracic Society·Terri E Weaver, Ronald R Grunstein
Jan 9, 2009·The European Respiratory Journal·D DamjanovicS Sorichter
Sep 29, 2009·European Journal of Internal Medicine·Anastasia AmfilochiouVlasios Polychronopoulos
Dec 17, 2009·American Journal of Respiratory and Critical Care Medicine·Ferran BarbéUNKNOWN Spanish Sleep and Breathing Group
Sep 2, 2010·Thorax·Malcolm KohlerJohn R Stradling
Nov 26, 2010·BMJ : British Medical Journal·Joaquín Durán-CantollaUNKNOWN Spanish Sleep and Breathing Group
Jun 2, 2011·Sleep·Alexandra ValentinSairam Parthasarathy
Jan 25, 2012·Patient Preference and Adherence·Carla Dias BarbosaDiana Rofail
Jan 31, 2012·Sleep & Breathing = Schlaf & Atmung·Alison J WimmsAdam V Benjafield
Oct 16, 2012·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Sydney B MontesiJessie P Bakker
Feb 12, 2013·The European Respiratory Journal·Francisco Campos-RodriguezNicolas Peña-Griñan
May 22, 2013·PloS One·Jean Christian BorelUNKNOWN Scientific Council of The Sleep Registry of the French Federation of Pneumology (OSFP)
Jan 23, 2015·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Rafaela Garcia Santos de AndradeGeraldo Lorenzi-Filho

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.