Impact of disease progression on health status, quality of life and costs in rheumatoid arthritis in Hungary

Orvosi hetilap
Márta PéntekLászló Gulácsi

Abstract

Rheumatoid arthritis (RA) is a chronic, progressive polyarthritis leading to substantial disability. Standardised data on consequences of disease progression are needed for clinical assessments and also for cost-effectiveness models. To analyse the impact of disease progression on health status, disease specific quality of life and costs in Hungary. A cross-sectional survey was performed between April and August, 2004, involving consecutive RA patients of 6 hospital based rheumatology outpatient centres. Self-completed questionnaires were used to assess functional (HAQ) and health status (EQ-5D), quality of life (RAQoL). Disease activity (DAS) and costs were also surveyed, statistical analysis was performed. 255 patients were involved [mean age 55.5 +/- 12.3 years; disease duration 9.0 +/- 9.3 years; HAQ 1.38 +/- 0.76; EQ-5D 0.46 +/- 0.33; RAQoL 16.2 +/- 8.1; DAS 5.09 +/- 1.42; costs 1,043,163 (+/- 844,750) HUF/patient/year, conversion 1 Euro = 250 HUF]. Correlation was significant between the parameters ( p < 0.01): EQ-5D index = 1.014 - 0.25 x HAQ-0.041 x DAS; HAQ = 0.314 + 0.065 x RAQoL. Analysis by disease severity levels (HAQ groups 0.5 difference) revealed that health status worsens (mean EQ-5D: 0.784; 0.576; 0.504; 0.367...Continue Reading

References

Sep 28, 2004·International Journal of Technology Assessment in Health Care·László GulácsiMichael Drummond
Jul 29, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Carlo A MarraAslam H Anis
Dec 14, 2005·Annals of the Rheumatic Diseases·Y ShoenfeldP-L Meroni
Oct 14, 2006·Annals of the Rheumatic Diseases·D E FurstM H Weisman
Mar 3, 2007·Clinical Rheumatology·Eva PalkonyaiEszter Meszaros
Apr 14, 2007·Orvosi hetilap·László Tamási, Zoltán Szekanecz
Oct 2, 2007·Orvosi hetilap·Valentin BrodszkyLászló Gulácsi

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Citations

Apr 22, 2009·Rheumatology International·Valentin BrodszkyLászló Gulácsi
Apr 16, 2009·International Journal of Technology Assessment in Health Care·András Inotai, Agnes Mészáros
Sep 24, 2015·Expert Review of Clinical Immunology·László GulácsiMárta Péntek
Jul 31, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Fanni RenczMárta Péntek
May 17, 2014·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Cs Zoltán HorváthImre Boncz

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