Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry)

The American Journal of Cardiology
Ronald CaputoJohn J Lopez

Abstract

In randomized trials, longer drug-eluting stent (DES) length has been associated with adverse clinical events. We used data from the EVENT registry to examine the impact of DES length on outcomes in routine clinical practice. We identified 5,425 unselected consecutive patients from the EVENT registry who had a single vessel treated with DES for nonemergency indications from 2004 through 2007. The association between stented length and short- and long-term outcomes was analyzed in ordinal categories (<15, 15 to 19, 20 to 24, and >24 mm) and as a continuous variable. There were few differences in baseline characteristics across categories. At 1 year, there was a stepwise increase in major adverse cardiac events (composite of death, myocardial infarction [MI], and target lesion revascularization [TLR]) with increasing stent length (8.0%, 10.1%, 11.8%, and 14.8%, p <0.001) and a similar relation with TLR (3.0%, 3.1%, 3.3%, and 5.0%, p = 0.02). After adjusting for demographic, clinical, angiographic, and treatment characteristics, longer stent length remained associated with 1-year major adverse cardiac events (adjusted hazard ratio 1.17 per 10-mm increase stent length) and TLR (hazard ratio 1.20 per 10 mm), but not with stent throm...Continue Reading

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Citations

Mar 8, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Bo XuUNKNOWN SEEDS Investigators
Jun 10, 2016·International Journal of Endocrinology and Metabolism·Mahnaz BarkhordariMohammadreza Bozorgmanesh
Jan 1, 2013·The American Journal of Cardiology·Jung-Min AhnSeung-Jung Park
Oct 27, 2015·Cardiovascular Intervention and Therapeutics·Hirokazu KonishiHiroyuki Daida
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Jan 13, 2015·Journal of cardiology·Masahide NaganoUNKNOWN Kumamoto Intervention Conference Study (KICS) Investigators
Oct 26, 2018·Circulation. Cardiovascular Interventions·Neal S Kleiman
Sep 24, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Min Gyu KongUNKNOWN Collaborators

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