Impact of Elective Percutaneous Coronary Intervention on Global Absolute Coronary Flow and Flow Reserve Evaluated by Phase-Contrast Cine-Magnetic Resonance Imaging in Relation to Regional Invasive Physiological Indices

Circulation. Cardiovascular Interventions
Yoshihisa KanajiTsunekazu Kakuta

Abstract

Few studies have documented changes in global absolute coronary blood flow and global coronary flow reserve after percutaneous coronary intervention (PCI) in relation to regional physiological measures. Phase-contrast cine-magnetic resonance of the coronary sinus is a promising approach to quantify global absolute coronary blood flow. We aimed to assess the impact of elective PCI on global absolute coronary blood flow and global coronary flow reserve by quantifying coronary sinus flow (CSF) using phase-contrast cine-magnetic resonance in relation to regional physiological indices. We prospectively studied 54 patients with stable angina undergoing elective PCI for a single proximal lesion. Phase-contrast cine-magnetic resonance was used to assess CSF and CSF reserve at rest and during maximum hyperemia, before and after PCI. Regional physiological indices were obtained during PCI. A complete data set was obtained in 50 patients. Hyperemic CSF increased significantly after PCI (pre-PCI, 230.2 [167.4-282.8] mL/min; post-PCI, 267.4 [224.1-346.2] mL/min; P<0.01), although 12 patients (24.0%) showed a decrease, despite successful PCI and improved fractional flow reserve. CSF reserve numerically, albeit not statistically significant (...Continue Reading

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Oct 19, 2017·Circulation. Cardiovascular Interventions·Yoshihisa KanajiTsunekazu Kakuta

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Citations

Jul 15, 2018·Circulation. Cardiovascular Interventions·Ziad A Ali, J Jane Cao
Jan 3, 2021·Journal of cardiology·Junji MatsudaTsunekazu Kakuta
Jul 7, 2020·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Rikuta HamayaUNKNOWN Collaborators
Aug 20, 2021·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Shingo KatoDaisuke Utsunomiya
Dec 14, 2021·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Toru MisawaTsunekazu Kakuta

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