Impact of endovascular options on lower extremity revascularization in young patients

Journal of Vascular Surgery
Cassius Iyad Ochoa ChaarRabih A Chaer

Abstract

This study assessed outcomes of revascularization strategies in young patients with premature arterial disease. Lower extremity revascularization outcomes from 2000 to 2008 were retrospectively compared among consecutive patients with comparable indications and procedures: age <50 years (group A) at the time of revascularization, 51 to 60 years (group B), and >60 years (control group C). Patency, limb salvage, and survival by limb or patient level were assessed by Kaplan-Meier and Cox proportional hazards analyses. A total of 409 limbs in 298 patients were treated: 44% for claudication and 56% for critical limb ischemia (CLI). Group A patients were more likely to be smokers and have a hypercoagulable state but less likely to have diabetes and renal failure. Treatment indications were comparable among groups, and procedures were equally distributed between open surgical and endovascular interventions. Two perioperative deaths occurred in group C (2%). Mean follow-up was 29 months, and 16% of claudicant patients in group A progressed to CLI (B, 3%; C, 2%; P < .001). Overall, 2-year primary, primary assisted, and secondary patency were significantly lower in group A (50.5%, 65.2%, 68.2%; P = .045) vs B (65.7%, 81.4%, 86.8%; P = .0...Continue Reading

References

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Citations

Apr 11, 2014·Annals of Vascular Diseases·Raffaele PulliCarlo Pratesi
Nov 30, 2014·Annals of Vascular Surgery·Francesco SpinelliFrancesco Stilo
Mar 18, 2016·Vascular and Endovascular Surgery·Francesco De SantisGuido Martini
Jun 6, 2017·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Christian UhlUNKNOWN The CRITISCH collaborators
Sep 15, 2020·Annals of Vascular Surgery·Tanner I KimCassius Iyad Ochoa Chaar
Dec 26, 2018·Journal of Vascular Surgery·Jose Ignacio TorrealbaRebecca Kelso

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