Impact of exclusion criteria on case mix, outcome, and length of stay for the severity of disease scoring methods in common use in critical care

Journal of Critical Care
Hannah WunschKathy Rowan

Abstract

To identify the exclusion criteria for the major severity of disease scoring methods in critical care and to investigate the impact of the exclusion criteria on the case mix, outcomes and length of stay for admissions to intensive care units (ICUs) in England, Wales and Northern Ireland. Cohort study-analysis of prospectively collected data. 127 adult, general (mixed medical/surgical) ICUs in England, Wales and Northern Ireland. 120,503 admissions between 1995 and 2001. None. Thirteen different exclusion criteria were identified from the original methodological/validation papers and data collection manuals for APACHE II, APACHE III, SAPS II and MPM II. Application of the original exclusion criteria for the four, major severity of disease scoring methods resulted in exclusion of between 11.5% and 14.6% of admissions. Hospital mortality for the overall cohort was 29.0% but ranged from 4.7% to 50.1% among those groups excluded. After application of the exclusion criteria for each scoring method, there was little difference in overall hospital mortality or median ICU and hospital length of stay for the included admissions when compared with the original cohort. At the level of individual ICUs, there were differences in hospital mor...Continue Reading

References

Dec 5, 1990·JAMA : the Journal of the American Medical Association·E L HannanE P Shields
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Mar 1, 1986·Annals of Internal Medicine·W A KnausJ E Zimmerman
Nov 24, 1993·JAMA : the Journal of the American Medical Association·S LemeshowJ Rapoport
May 1, 1996·Intensive Care Medicine·D R Goldhill, P S Withington
Nov 6, 1998·Intensive Care Medicine·R J BosmanD F Zandstra
Jun 23, 1999·Chest·A MichalopoulosS Geroulanos
Mar 29, 2001·Intensive Care Medicine·M SuistomaaJ Takala

❮ Previous
Next ❯

Citations

Jan 12, 2010·International Journal of Technology Assessment in Health Care·Sheila HarveyNick Black
Apr 2, 2008·Critical Care Medicine·Marta L RenderTimothy P Hofer
Oct 29, 2005·Journal of Critical Care·Hannah WunschKathryn Rowan
Jan 19, 2017·Critical Care Medicine·Andrew A Kramer
Sep 13, 2008·Current Opinion in Critical Care·David A Harrison, Kathryn M Rowan
Jun 3, 2009·Waste Management & Research : the Journal of the International Solid Wastes and Public Cleansing Association, ISWA·Martin van PraaghPatrik Karlsson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.