Impact of exercise on hippocampal neurogenesis in hyperglycemic diabetes

Journal of Exercise Rehabilitation
Chae-Bin Lee, Seung-Soo Baek

Abstract

Hyperglycemic diabetes is a chronic metabolic disorder characterized by high level of plasma glucose. Numerous studies have shown that hy-perglycemic diabetes leads to brain dysfunction including cognitive im-pairment and emotional disorders. This study evaluated the impact of exercise on brain dysfunction, hippocampal neurogenesis, and cogni-tive impairment in hyperglycemic diabetes. The present study suggests that exercise improves hyperglycemic control and prevents decline of cognition through increasing hippocampal neurogenesis. Understanding the mechanism of exercise for hippocampal neurogenesis can lead to the development of therapeutic strategies for metabolic disorders.

References

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May 18, 2013·Neuroscience and Biobehavioral Reviews·Nancy HoIrwin Lucki
Jul 26, 2014·Journal of Exercise Rehabilitation·Yu-Mi HeoSeung-Soo Baek
Sep 12, 2014·Journal of Exercise Rehabilitation·Suh-Jung Kang
Apr 14, 2015·The Lancet. Diabetes & Endocrinology·Nawab QizilbashStuart J Pocock
Oct 2, 2015·Aging and Disease·João M N Duarte
Nov 4, 2016·Journal of Exercise Rehabilitation·Seung-Soo Baek
Mar 8, 2018·Journal of Exercise Rehabilitation·Jae-Min LeeYoung-Pyo Kim

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