PMID: 6407089Jan 1, 1983Paper

Impact of factor VIII deficiency on clotting factor utilization in the United States

La Ricerca in Clinica E in Laboratorio
Louis AledortS S Shapiro

Abstract

In a study of 1,551 hemophiliacs over a 4-year period of time, factor VIII utilization was assessed. It is clear that factor VIII usage is a function of severity of disease and therapeutic program. The average amount of factor VIII used per patient was 39,880 U/year. Patients selected for home care, use significantly more than those patients not on home care. As much as 101,000 U/year are used by a small number of patients on prophylaxis. These data can be used in predicting source plasma requirements for annual national use as well as costs.

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