Impact of FDG PET in optimizing patient selection for cytoreductive surgery in recurrent ovarian cancer

European Journal of Nuclear Medicine and Molecular Imaging
Yasuhiko EbinaNoriaki Sakuragi

Abstract

To investigate the impact of PET and PET/CT scanning on decision-making in management planning and to identify the optimal setting for selecting candidates for surgery in suspicious recurrent ovarian cancer. A retrospective chart review was performed in patients with possible recurrent ovarian cancer after primary optimal cytoreduction and taxane/carboplatin chemotherapy who had undergone FDG PET or FDG PET/CT scans from July 2002 to August 2008 to help make treatment decisions. The analysis included 44 patients who had undergone a total of 89 PET scans. The positive PET scans were classified as follows. (1) localized (one or two localized sites of FDG uptake), (2) multiple (three or more sites of FDG uptake), (3) diffuse (extensive low-grade activity outlining serosal and peritoneal surfaces). Of the 89 PET scans, 52 (58.4%) led to a change in management plan. The total number of patients in whom cytoreductive surgery was selected as the treatment of choice increased from 12 to 35. Miliary disseminated disease, which was not detected by PET scan, was found in 22.2% of those receiving surgery. Miliary disseminated disease was detected in 6 of the 12 patients with recurrent disease whose treatment-free interval (TFI) was <12 mon...Continue Reading

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Citations

May 28, 2014·Best Practice & Research. Clinical Obstetrics & Gynaecology·Antonia Carla TestaVittoria Rufini
Apr 20, 2014·Japanese Journal of Radiology·Kazuhiro KitajimaKazuro Sugimura
Oct 1, 2014·Cancers·Andrea GallaminiAnna Borra
Jun 9, 2015·Seminars in Nuclear Medicine·Swapnil BagadeFarrokh Dehdashti
Sep 20, 2016·Obstetrical & Gynecological Survey·Jorge Daniel Oldan, Parth S Patel
Feb 10, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Benjapa KhiewvanAbass Alavi
May 22, 2020·Journal of Ovarian Research·Tung Tung TsoiElaine Y P Lee
Jun 20, 2020·AJR. American Journal of Roentgenology·Elaine Y P LeePek-Lan Khong
Sep 9, 2017·The Journal of Obstetrics and Gynaecology Research·Hideaki Tsuyoshi, Yoshio Yoshida
Oct 22, 2019·Seminars in Nuclear Medicine·Jukka KemppainenMarko Seppänen

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