Prenatal diagnosis of congenital heart disease is now well established for a wide range of cardiac anomalies. Diagnosis of congenital heart disease during fetal life not only identifies the cardiac lesion but may also lead to detection of associated abnormalities. This information allows a detailed discussion of the prognosis with parents. For continuing pregnancies, appropriate preparation can be made to optimize the postnatal outcome. Reduced morbidity and mortality, following antenatal diagnosis, has been reported for coarctation of the aorta, hypoplastic left heart syndrome, and transposition of the great arteries. With regard to screening policy, most affected fetuses are in the "low risk" population, emphasizing the importance of appropriate training for those who undertake such obstetric anomaly scans. As a minimum, the four chamber view of the fetal heart should be incorporated into midtrimester anomaly scans, and where feasible, views of the outflow tracts should also be included, to increase the diagnostic yield. Newer screening techniques, such as measurement of nuchal translucency, may contribute to identification of fetuses at high risk for congenital heart disease and prompt referral for detailed cardiac assessment.
Screening for congenital heart disease prenatally. Results of a 2 1/2-year study in the South East Thames Region
Effect of detailed fetal echocardiography as part of routine prenatal ultrasonographic screening on detection of congenital heart disease
Using fetal nuchal translucency to screen for major congenital cardiac defects at 10-14 weeks of gestation: population based cohort study
Detection of transposition of the great arteries in fetuses reduces neonatal morbidity and mortality
Comparison of outcome when hypoplastic left heart syndrome and transposition of the great arteries are diagnosed prenatally versus when diagnosis of these two conditions is made only postnatally
Current and potential impact of fetal diagnosis on prevalence and spectrum of serious congenital heart disease at term in the UK. British Paediatric Cardiac Association
World experience of percutaneous ultrasound-guided balloon valvuloplasty in human fetuses with severe aortic valve obstruction
Prenatal diagnosis of congenital heart disease in the northern region of England: benefits of a training programme for obstetric ultrasonographers
Early screening for fetal cardiac anomalies by transvaginal echocardiography in an unselected population: the role of operator experience
Accuracy and limitations of transabdominal fetal echocardiography at 12-15 weeks of gestation in a population at high risk for congenital heart disease
Limitations of using first-trimester nuchal translucency measurement in routine screening for major congenital heart defects
Evaluation of prenatal diagnosis of associated congenital heart diseases by fetal ultrasonographic examination in Europe
Different policies on prenatal ultrasound screening programmes and induced abortions explain regional variations in infant mortality with congenital malformations
Examination of the fetal heart by five short-axis views: a proposed screening method for comprehensive cardiac evaluation
Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registries
Impact of prenatal diagnosis on survival and early neurologic morbidity in neonates with the hypoplastic left heart syndrome
The use of nuchal translucency measurement and second trimester biochemical markers in screening for Down's syndrome
Incidence of major structural cardiac defects associated with increased nuchal translucency but normal karyotype
Review of diagnosis, treatment, and outcome of fetal atrial flutter compared with supraventricular tachycardia
Spatio-temporal image correlation (STIC): a new tool for the prenatal screening of congenital heart defects
Three-dimensional (3D) and 4D color Doppler fetal echocardiography using spatio-temporal image correlation (STIC)
Creation of an atrial septal defect in utero for fetuses with hypoplastic left heart syndrome and intact or highly restrictive atrial septum
Transplacental fetal treatment improves the outcome of prenatally diagnosed complete atrioventricular block without structural heart disease
Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of successful intervention
Prenatal diagnosis of congenital heart disease using four-dimensional spatio-temporal image correlation (STIC) telemedicine via an Internet link: a pilot study
Nuchal translucency and fetal cardiac defects: a pooled analysis of major fetal echocardiography centers
Letter regarding article by Jaeggi et al, "transplacental fetal treatment improves the outcome of prenatally diagnosed complete atrioventricular block without structural heart disease"
Prenatal diagnosis of complete atrioventricular block associated with structural heart disease: combined experience of two tertiary care centers and review of the literature
Clinical and socioeconomic predictors of pregnancy termination for fetuses with congenital heart defects: a population-based evaluation
Detection of congenital heart defects throughout pregnancy; impact of first trimester ultrasound screening for cardiac abnormalities
Incidence of antenatal moderate and severe congenital cardiac anomalies in Cairo (a multi-center retrospective study)
An exploration of the potential utility of fetal cardiovascular MRI as an adjunct to fetal echocardiography
Parents' request for termination of pregnancy due to a congenital heart defect of the fetus in a country with liberal interruption laws.
Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer
Prenatal diagnosis and planned peri-partum care as a strategy to improve pre-operative status in neonates with critical CHDs in low-resource settings: a prospective study
A low threshold for neonatal intervention yields a high rate of biventricular outcomes in pulmonary atresia with intact ventricular septum
Outcomes of Infants with Prenatally Diagnosed Congenital Heart Disease Delivered in a Tertiary-care Pediatric Cardiac Facility
3D/4D spatiotemporal image correlation (STIC) fetal echocardiography provides incremental benefit over 2D fetal echocardiography in predicting postnatal surgical approach in double-outlet right ventricle.
Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.
Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.