Impact of Florida's prescription drug monitoring program and pill mill law on high-risk patients: A comparative interrupted time series analysis

Pharmacoepidemiology and Drug Safety
Hsien-Yen ChangG Caleb Alexander

Abstract

We quantified the effects of Florida's prescription drug monitoring program and pill mill law on high-risk patients. We used QuintilesIMS LRx Lifelink data to identify patients receiving prescription opioids in Florida (intervention state, N: 1.13 million) and Georgia (control state, N: 0.54 million). The preintervention, intervention, and postintervention periods were July 2010 to June 2011, July 2011 to September 2011, and October 2011 to September 2012. We identified 3 types of high-risk patients: (1) concomitant users: patients with concomitant use of benzodiazepines and opioids; (2) chronic users: long-term, high-dose, opioid users; and (3) opioid shoppers: patients receiving opioids from multiple sources. We compared changes in opioid prescriptions between Florida and Georgia before and after policy implementation among high-risk/low-risk patients. Our monthly measures included (1) average morphine milligram equivalent per transaction, (2) total opioid volume across all prescriptions, (3) average days supplied per transaction, and (4) total number of opioid prescriptions dispensed. Among opioid-receiving individuals in Florida, 6.62% were concomitant users, 1.96% were chronic users, and 0.46% were opioid shoppers. Followi...Continue Reading

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Citations

Sep 11, 2018·Anesthesia and Analgesia·Brittany N BurtonRodney A Gabriel
Oct 9, 2020·The Journal of Pain : Official Journal of the American Pain Society·Yun ShenAmie J Goodin
Feb 26, 2021·British Journal of Clinical Pharmacology·Juliana de Oliveira CostaSallie-Anne Pearson
Apr 11, 2021·Journal of Clinical Epidemiology·Hemalkumar B MehtaG Caleb Alexander
Nov 26, 2019·Drug and Alcohol Dependence·Jackie Yenerall, Melinda B Buntin
Dec 22, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Chris DelcherHenry W Young

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