Impact of functional status on survival after coronary artery bypass grafting in a veteran population

The Annals of Thoracic Surgery
Roberto CerveraDanny Chu

Abstract

Although functional impairment has been shown to be an adverse outcome of frailty, little is known of its effect on patients after cardiac operations. We aimed to assess the effect of limited functional status on long-term survival after coronary artery bypass grafting (CABG). We reviewed prospectively gathered data from 1,503 consecutive patients who underwent isolated CABG between 1997 and 2009. We compared the outcomes of 318 patients with limited functional status and 1,185 patients without any functional impairment. The mean follow-up period was 65 months (range, 1 to 157 months). We assessed the relationship between functional status impairment and long-term survival by Cox regression analysis adjusted for confounding factors. Functionally impaired patients were slightly older (63±9 vs 62±8 years, p=0.05) and had more risk factors for adverse outcomes than patients who were functionally unimpaired. After adjustment for potential confounding variables by multivariate logistic regression analysis, preoperative limited functional status was not an independent predictor (odds ratio [95% confidence interval]) of 30-day mortality (1.4 [0.3 to 5.8], p=0.67) or major adverse cardiac events (1.3 [0.5 to 3.3], p=0.71), nor was it p...Continue Reading

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Citations

Jun 24, 2016·European Journal of Preventive Cardiology·Claudio MarcassaPantaleo Giannuzzi
Jan 8, 2016·Annals of the Royal College of Surgeons of England·K OaklandP A Coughlin
Sep 16, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Caroline BäckChristian H Møller
Jun 27, 2021·Journal of Cardiothoracic Surgery·Jessica Avery LeeUNKNOWN Canadian Cardiovascular Surgery Meta-Analysis Working Group

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