Impact of gas(less) laparoscopy and laparotomy on peritoneal tumor growth and abdominal wall metastases

Annals of Surgery
N D BouvyH J Bonjer

Abstract

A tumor model in the rat was used to study peritoneal tumor growth and abdominal wall metastases after carbon dioxide (CO2) pneumoperitoneum, gasless laparoscopy, and laparotomy. The role of laparoscopic resection of cancer is under debate. Insufflation of the peritoneal cavity with CO2 is believed to be a causative factor in the development of abdominal wall metastases after laparoscopic resection of malignant tumors. In the solid tumor model, a lump of 350-mg CC-531 tumor cells was placed intraperitoneally in rats having CO2 pneumoperitoneum (n = 8), gasless laparoscopy (n = 8), or conventional laparotomy (n = 8). After 20 minutes, the solid tumor was removed through a laparoscopic port or through the laparotomy. In the cell seeding model, 5 x 10(5) CC-531 cells were injected intraperitoneally before CO2 pneumoperitoneum (n = 12), gasless laparoscopy (n = 12), or laparotomy (n = 12). All operative procedures lasted 20 minutes. After 6 weeks, in the solid tumor model and after 4 weeks in the cell seeding model, tumor growth was scored semiquantitatively. All results were analyzed using the analysis of variance. In the solid tumor model, peritoneal tumor growth in the laparotomy group was greater than in the CO2 pneumoperitoneu...Continue Reading

References

Dec 1, 1992·Annals of Surgery·E H PhillipsD Rosenthal
Nov 1, 1990·Annals of Surgery·G Berci, J Sackier
Jan 1, 1990·Annals of Surgery·F DuboisH Levard
Jul 1, 1990·Diseases of the Colon and Rectum·H ZirngiblP Hermanek
Jan 1, 1988·British Journal of Cancer·P MurphyI Taylor
Sep 1, 1983·Diseases of the Colon and Rectum·E S HughesW R Johnson
Nov 1, 1983·Gastrointestinal Endoscopy·G MinoliG Tadeo
Aug 1, 1994·Diseases of the Colon and Rectum·V A BotomanR C Thirlby
Nov 1, 1995·Diseases of the Colon and Rectum·D B JonesJ W Fleshman
May 1, 1995·The British Journal of Surgery·J P GriffithM J McMahon
Aug 1, 1995·The British Journal of Surgery·G KazemierJ F Lange
May 1, 1995·Diseases of the Colon and Rectum·J M RamosR T Schlinkert
Mar 1, 1995·The British Journal of Surgery·S D Wexner, S M Cohen
Aug 7, 1993·Lancet·L FligelstoneD Crosby
Jun 1, 1994·Annals of Surgery·R C FrazeeJ B Harrison
Jun 1, 1994·Annals of Surgery·G C HoffmanJ H Vansant
Feb 1, 1994·Diseases of the Colon and Rectum·R W Beart

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Citations

Dec 17, 1997·International Journal of Cancer. Journal International Du Cancer·B C van der WalC H van Eijck
May 8, 2000·Journal of Cellular Biochemistry·M D BassonB E Sumpio
May 20, 1999·Seminars in Surgical Oncology·D B PearlstoneP F Mansfield
Nov 7, 2000·Journal of Surgical Oncology·P G Jackson, S R Evans
Apr 22, 1999·Diseases of the Colon and Rectum·S J NeuhausG G Jamieson
Jun 27, 2007·European Journal of Nutrition·Carsten N GuttMarkus W Büchler
Aug 7, 2002·Surgical Endoscopy·E J Hazebroek, UNKNOWN Color Study Group
Oct 1, 2004·Surgical Endoscopy·R VeldkampUNKNOWN European Association of Endoscopic Surgery (EAES)
May 8, 2007·Surgical Endoscopy·T M Young-FadokD B Earle
May 19, 2001·Surgical Endoscopy·J E HartleyJ R Monson
Jul 10, 2001·Surgical Endoscopy·O ZmoraS D Wexner
Jul 10, 2001·Surgical Endoscopy·C BalagueC A Jacobi
Jul 10, 2001·Surgical Endoscopy·M ProssH U Schulz
Jul 10, 2001·Surgical Endoscopy·T SuematsuS Kitano
Nov 1, 2005·Journal of Hepato-biliary-pancreatic Surgery·Hideo YamamotoYuji Nimura
May 2, 2006·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Fernando Delgado GomisJosé M Guallar Rovira
Feb 1, 2009·The Indian Journal of Surgery·Sanjeev SinglaSushil Budhiraja
Jun 5, 2013·The Indian Journal of Surgery·Sivaprakash RathanaswamySameer Gupta
May 21, 2005·Journal of Minimally Invasive Gynecology·Ludovico MuziiPierluigi Benedetti Panici
Mar 12, 2004·The Journal of Surgical Research·Jennefer A Kieran, Myriam J Curet
Jun 26, 2009·Journal de chirurgie·K SlimP Valleur
Oct 8, 2003·Gynecologic Oncology·Pedro T RamirezCharles Levenback
Jul 27, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·F LécuruR Taurelle
Aug 21, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·A AgostiniF Lécuru
Aug 9, 2003·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M KilianF A Wenger
Nov 5, 1999·Journal of the American College of Surgeons·E J Nieveen van DijkumD J Gouma
Dec 10, 2003·The Lancet Oncology·J C CoffeyH P Redmond
Oct 2, 2001·The British Journal of Surgery·A Gupta, D I Watson
Jul 17, 1998·The British Journal of Surgery·S J NeuhausD I Watson
Aug 12, 1999·The Australian and New Zealand Journal of Surgery·R A Allardyce
Mar 4, 2000·The Australian and New Zealand Journal of Surgery·D I WatsonG G Jamieson

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