Impact of Hospital Bed Shortages on the Containment of COVID-19 in Wuhan

International Journal of Environmental Research and Public Health
Weike ZhouSanyi Tang

Abstract

The global outbreak of COVID-19 has caused worrying concern amongst the public and health authorities. The first and foremost problem that many countries face during the outbreak is a shortage of medical resources. In order to investigate the impact of a shortage of hospital beds on the COVID-19 outbreak, we formulated a piecewise smooth model for describing the limitation of hospital beds. We parameterized the model while using data on the cumulative numbers of confirmed cases, recovered cases, and deaths in Wuhan city from 10 January to 12 April 2020. The results showed that, even with strong prevention and control measures in Wuhan, slowing down the supply rate, reducing the maximum capacity, and delaying the supply time of hospital beds all aggravated the outbreak severity by magnifying the cumulative numbers of confirmed cases and deaths, lengthening the end time of the pandemic, enlarging the value of the effective reproduction number during the outbreak, and postponing the time when the threshold value was reduced to 1. Our results demonstrated that establishment of the Huoshenshan, Leishenshan, and Fangcang shelter hospitals avoided 22,786 people from being infected and saved 6524 lives. Furthermore, the intervention of...Continue Reading

References

Oct 22, 2002·Mathematical Biosciences·P van den Driessche, James Watmough
Feb 10, 2006·Mathematical Biosciences·Wendi Wang
Jun 24, 2008·Journal of Theoretical Biology·Simeone MarinoDenise E Kirschner
Nov 1, 2018·Mathematical Biosciences and Engineering : MBE·Aili WangHuaiping Zhu
Dec 13, 2018·Bulletin of Mathematical Biology·Aili WangRobert Smith
Jan 30, 2020·The New England Journal of Medicine·Qun LiZijian Feng
Feb 13, 2020·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Jantien A BackerJacco Wallinga
Jul 17, 2020·Nature·Xingjie HaoChaolong Wang
Jul 22, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Biao TangJianhong Wu
Dec 10, 2020·Bulletin of the World Health Organization·Juan LiHuaiping Zhu

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Citations

Apr 2, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Hiroyuki NaganoYuichi Imanaka

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Software Mentioned

fmincon
MATLAB

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