Impact of IL-1 genotype and smoking status on the prognosis of osseointegrated implants

Clinical Oral Implants Research
Boris GruicaDaniel Buser

Abstract

This study evaluated the impact of the IL-1 genotype and smoking status on the prognosis and development of complications of osseointegrated implants. The clinical charts of 180 consecutively admitted patients were analyzed with respect to the occurrence of biological complications in conjunction with oral implants. Biologic complications were defined as clinical conditions with suppuration from the peri-implant sulcus, development of a fistula or peri-implantitis with radiologic bone loss. All patients had received one or more ITI dental implants, which had been in function for at least 8 (range: 8-15) years. This patient population had received 292 implants. From these, 51 implants in 34 patients showed late (infectious) biologic complications, and 241 implants had survived without any biologic complications at all. Of the 180 patients, 53 were smokers, who were subdivided in a series of classes according to their intensity of smoking and 127 were never smokers. Sixty-four of 180 (36%) patients tested positive for the IL-1 genotype polymorphism. This prevalence corresponds to previous reports for the prevalence of European descent populations. The results for the non-smoking group indicated no significant correlation between ...Continue Reading

References

Dec 1, 1992·Clinical Oral Implants Research·H P WeberR C Williams
Aug 1, 1991·Journal of Periodontology·P StashenkoS S Socransky
Dec 1, 1987·Oral Microbiology and Immunology·A MombelliN P Land
Jan 1, 1997·Journal of Clinical Periodontology·K S KornmanG W Duff
Nov 1, 1996·Annals of Periodontology·S Offenbacher
Jun 1, 1993·Periodontology 2000·R J Genco, H Löe
Oct 31, 1998·Journal of Clinical Periodontology·E A GoreG M Galbraith
Mar 11, 2000·Journal of Periodontology·M J McDevittK S Kornman
Feb 4, 2003·Clinical Oral Implants Research·Andreas FeloutzisKenneth S Kornman

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Citations

Jan 6, 2006·Mund-, Kiefer- und Gesichtschirurgie : MKG·A Rabel, S G Köhler
Mar 16, 2007·Implant Dentistry·Debby Hwang, Hom-Lay Wang
May 21, 2005·Clinical Implant Dentistry and Related Research·Henrik JanssonGunilla Bratthall
Mar 3, 2012·Journal of Investigative and Clinical Dentistry·Tung Nguyen-HieuGérard Aboudharam
May 25, 2007·The Journal of Oral Implantology·Dennis Flanagan
Sep 5, 2014·Head & Face Medicine·Ralf SmeetsJamal M Stein
Sep 27, 2014·British Dental Journal·A Alani, K Bishop
Dec 2, 2014·Dental Clinics of North America·Dolphus R Dawson, Samuel Jasper
Dec 2, 2014·Dental Clinics of North America·Georgios E RomanosJosé Luis Calvo-Guirado
Jan 1, 2014·International Journal of Oral and Maxillofacial Surgery·M ClementiniL Canullo
Feb 22, 2012·Journal of Endodontics·Alejandro Iglesias-LinaresEnrique Solano-Reina
Oct 24, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Ying-He LinPing Gong
Jul 5, 2006·Dental Clinics of North America·David W PaquetteRay C Williams
Sep 1, 2005·Journal of Clinical Periodontology·Lior ShapiraDenis F Kinane
Aug 9, 2008·Australian Dental Journal·L J A Heitz-Mayfield
Nov 6, 2008·Clinical Oral Implants Research·G Huynh-BaG E Salvi
Sep 14, 2006·Clinical Oral Implants Research·Andrea Mombelli, Norbert Cionca
Sep 18, 2007·Clinical Oral Implants Research·Ioannis K KaroussisIoannis Fourmousis
Feb 5, 2009·Clinical Oral Implants Research·Claudia Cristina MontesPaula Cristina Trevilatto
Aug 16, 2006·Clinical Oral Implants Research·Marja L LaineStefan Renvert
Sep 9, 2008·Journal of Clinical Periodontology·Lisa J A Heitz-Mayfield
May 19, 2007·Journal of Clinical Periodontology·Frank Peter StrietzelIngeborg Küchler
May 4, 2007·Periodontology 2000·Georgia K Johnson, Janet M Guthmiller
Dec 14, 2011·Clinical Oral Implants Research·Xanthippi DerekaNikolaos Donos
Jan 22, 2011·Clinical Oral Implants Research·Acir José DirschnabelPaula Cristina Trevilatto
Mar 19, 2011·Clinical Implant Dentistry and Related Research·Rafaela F MeloGlória M Thompson Galli
Nov 19, 2011·Clinical Oral Implants Research·P VazP Tavares
Jun 3, 2011·Clinical Oral Implants Research·Wil G M GeraetsPaul F van der Stelt
Apr 11, 2012·Clinical Oral Implants Research·Tomas LinkeviciusAlina Puriene
Dec 1, 2011·Australian Dental Journal·G Liddelow, I Klineberg
Oct 25, 2012·Clinical Oral Implants Research·Andrea MombelliNorbert Cionca
Jul 30, 2014·Clinical Implant Dentistry and Related Research·Jan CosynHugo De Bruyn

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