Abstract
In clinical studies, it has been found that treating asthmatic patients with inhaled corticosteroids can reduce the need for in-patient care. The purpose of this study was to determine if such a relationship could be observed in available health-care statistics in Sweden and, if such a relationship could be established, what health economic consequences it implied. A retrospective study was conducted using regional data on acute hospitalization-ie, number of bed-days in acute somatic in-patient care clinics-and sales of anti-asthmatic drugs from 14 health-care administrative regions, covering 6 million people (71% of the Swedish population) between 1978 and 1991. The data were analyzed in multiple regression analyses where time- and cross-section data were pooled. The variation in bed-days was explained by three variables: (1) the sales of inhaled corticosteroids, (2) the total number of bed-days within acute somatic in-patient care, and (3) the sales of inhaled bronchodilators, which were used as a proxy variable for asthma prevalence. The total number of bed-days due to asthma in the 14 county councils did not show any upward or downward trend between 1978 and 1985. However, after 1985, there was a significant downward trend ...Continue Reading
References
Sep 1, 1992·Drugs·R N Brogden, D McTavish
Mar 26, 1992·The New England Journal of Medicine·K B WeissT A Hodgson
Mar 1, 1992·Respiratory Medicine·B A OtulanaT Higenbottam
Sep 1, 1991·Journal of General Internal Medicine·M B BoltonL R Schultz
Jan 1, 1991·Social Science & Medicine·B Jönsson, P Carlsson
Aug 1, 1991·Thorax·P G BurneyW W Holland
Nov 30, 1989·The New England Journal of Medicine·P J Barnes
Jan 1, 1989·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N Aberg
Sep 12, 1987·Lancet·I F Hay, T W Higenbottam
Feb 27, 1988·Lancet·E Adelroth, S Thompson
Apr 1, 1995·Archives of Disease in Childhood·B J Perera
Oct 1, 1994·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·M R Sears, D R Taylor
Jan 1, 1994·Thorax·L LarssonM Uddenfeldt
Oct 13, 1994·The New England Journal of Medicine·E S FisherS M Sharp
Jan 1, 1993·Thorax·T J Marrie
Sep 5, 1993·PharmacoEconomics·M P Rutten-van MölkenF F Rutten
Jun 7, 1993·PharmacoEconomics·K B Weiss, S D Sullivan
Citations
Oct 15, 2009·European Journal of Clinical Pharmacology·Marianne Heibert ArnlindEva Wikström Jonsson
Dec 4, 2003·Clinical Therapeutics·Kenneth R Chapman
Dec 4, 2003·Clinical Therapeutics·David S Pearlman
Aug 22, 2001·Controlled Clinical Trials·S D SullivanUNKNOWN START Steering Committee
Aug 28, 1999·Journal of Clinical Epidemiology·C S LundborgV K Diwan
May 30, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Akerke BaibergenovaKira Leeb
Aug 9, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·John Oppenheimer
Nov 28, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Tina V HartertMarie R Griffin
Aug 31, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·D A Stempel
May 31, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·F AnderssonL Arheden
Mar 4, 1999·The New England Journal of Medicine·S B Soumerai, D Ross-Degnan
Mar 24, 2004·Disease Management : DM·Neil GoldfarbNicole Cobb
Feb 15, 2005·International Journal of Clinical Practice·B LindgrenUNKNOWN RELIEF study investigators
Jan 15, 2004·PharmacoEconomics·Ulf-G Gerdtham, Douglas Lundin
Dec 4, 2003·Clinical Therapeutics·David E Skoner
Jan 5, 2002·Pharmacoepidemiology and Drug Safety·C BeimfohrS K Weiland
Mar 10, 2016·JMIR Research Protocols·Andrew J CaveDavid W Johnson
Dec 20, 2003·Respiratory Medicine·D C Malone, A T Luskin
Feb 15, 2001·The Journal of Allergy and Clinical Immunology·S D Sullivan, K B Weiss
Aug 18, 2004·International Journal of Clinical Practice·A Gillissen
Nov 8, 2002·Pediatric Pulmonology·Talitha L FeenstraLiesbeth E M Van Essen-Zandvliet
Mar 20, 2003·Pharmacoepidemiology and Drug Safety·Chi-Yu ChenChun-Yuh Yang