Impact of laparoscopic radical hysterectomy on survival outcome in patients with FIGO stage IB cervical cancer: A matching study of two institutional hospitals in Korea

Gynecologic Oncology
Se Ik KimYong Beom Kim

Abstract

To compare survival outcomes of primary laparoscopic radical hysterectomy (LRH) and open radical hysterectomy (ORH) in patients with FIGO stage IB cervical cancer. We retrospectively identified stage IB1-IB2 cervical cancer patients who received either LRH (n = 343) or ORH (n = 222) at two tertiary institutional hospitals between 2000 and 2018. To adjust for confounders, we conducted Mahalanobis distance-based sample matching for stage, histology, cervical mass size, parametrial invasion, and lymph node metastasis. Then, survival outcomes were compared between the matched groups. Through the independent matching processes, we narrowed the study population to stage IB1 patients and stage IB1 patients with tumor size ≤2 cm on pre-operative MRI. After matching, LRH group showed poorer progression-free survival (PFS) than ORH group (3-year: 85.4% vs. 91.8%; P = 0.036), whereas no significant difference in overall survival (OS) was found. Regarding recurrence patterns, no significant differences in the incidences of pelvic, retroperitoneal lymph node and abdominal recurrences, or distant metastasis were observed between the two groups. Among the matched patients with stage IB1 who had cervical mass size ≤2 cm, the LRH and ORH groups...Continue Reading

Citations

Dec 10, 2019·Current Opinion in Obstetrics & Gynecology·Alexander Melamed, Pedro T Ramirez
Apr 12, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Xu ChenXiaojian Yan
May 28, 2020·Journal of Gynecologic Oncology·Giorgio BoganiFrancesco Raspagliesi
Jun 24, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ting Wen Yi HuZhengyu Li
Jul 24, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Junshen HeChunlin Chen
Jan 29, 2020·Current Oncology Reports·Stefano GreggiCono Scaffa
Aug 14, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Luis ChivaUNKNOWN SUCCOR study Group
May 26, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Giorgio BoganiFrancesco Raspagliesi
Nov 1, 2020·Annals of Surgical Oncology·Derman Basaran, Mario M Leitao
Jan 24, 2021·Archives of Gynecology and Obstetrics·Paolo GennariAtanas Ignatov
Jan 29, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Juliana RodriguezRene Pareja
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May 22, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Dimitrios NasioudisNawar A Latif
May 28, 2021·Gynecology and Minimally Invasive Therapy·Fan Chun YangZhongping Cheng
Jun 25, 2021·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Yuanyi YuShequn Gu
Jul 30, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Felix BoriaJuan Luis Alcazar

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